With experience gained from decades of serving the pharmaceutical industry, GEA has developed a well proven and robust range of PHARMA-SD® Spray Dryers. Our PHARMA-SD® range comprises a complete portfolio of GMP spray drying plants – ranging from the PSD-1 lab size units suitable for initial testing under GMP conditions and small ...

PHARMA-SD® 制药级喷雾干燥机从适用于在 cGMP 条件下进行测试和小规模生产的实验设备，一直可以扩大到具有 4,000 公斤/小时标称干燥气体速率的大规模生产装置。 GEA 还能提供具有高度密闭设计的 PHARMA-SD® 喷雾干燥机，可在满足OEL值低于 10 微克/立方米的情况下对高活性复合物进行安全的喷雾干燥。 这种设计在设备运行、收料和清洗期间能对人员进行有效的保护，从而营造安全的工作环境。 这使得制药公司能够充分利用喷雾干燥的优势，即使是面对高活性产 …

PHARMA-SD® type PSD-2 CC; closed cycle spray dryer. Atomization A liquid feed stock is “atomized” into droplets by means of a nozzle or rotary atomizer. Nozzles use liquid pressure or compressed gas to atomize the feed while rotary atomizers employ an …

The PSD offers a choice of three atomizer systems: rotary, co-current two-fluid nozzle, and fountain two-fluid nozzle. It dries both aqueous and solvent feedstocks safely. The dryer provides excellent access and is configured to be Cleaned - In - Place (CIP).

Added 7 new spray dryers – 5 GEA spray dryers in GMP and 2 for R&D. Become the only pharmaceutical CDMO in the world that implements the innovative PolarDry electrostatic spray …

Deucravacitinib于2022年9月在美国获批，用于治疗适合系统治疗或光疗的成年中重度斑块状银屑病患者，为全球首个获批的口服选择性酪氨酸激酶2（TYK2）变构抑制剂，商品名为Sotyktu，上市6 mg规格，口服片剂。 原研公司 百时美施贵宝 预测该药峰值销售可达40亿美元。 Deucravacitinib为BCS II类（低溶解性，高渗透性）药物，化合物溶解度呈现pH依赖性，pH越高，化合物的溶解度越低。 游离碱晶型在pH=1.05时，溶解度大于3 mg/mL，而pH=6.5时，溶 …

GEA PSD 2 – aqueous and organic solvent capable (≤ 70kg batches) --> Agitated vacuum dryer for secondary drying of spray dried powder. GEA PSD 4 – aqueous only – plans available for upgrade to solvent capability (80 – 500kg batches). GEA …

Esteve Química offers spray drying capability at the Celrà manufacturing site to complement API synthesis. Celrà offers both R&D and industrial cGMP scale spray drying capacity: • Laboratory scale Spray Dryer (Büchi B290) Typical batch size: 2 to 500g • PSD-1 Spray Dryer (GEA Niro)

修订后的《支付服务指令》 (PSD2) 是一项欧洲法规，旨在提高 线上付款 的安全性，同时支持金融服务领域的竞争。 PSD2 于 2016 年生效，是对 2007 年设立的原始 PSD 的更新。

The PSD2 is a medium-size equipment for clinical and commercial use, which can handle class-2 organic solvents and is designed to carry out the production of APIs and pre-formulated APIs (through spray drying in the presence of excipients, classified as drug product intermediates) with an OEL equal to or greater than 10 μg/m