2022年2月15日 · Previous studies by Johns Hopkins Medicine researchers showed that psychedelic treatment with psilocybin relieved major depressive disorder symptoms in adults for up to a month.

2022年11月2日 · In this phase 2 double-blind trial, we randomly assigned adults with treatment-resistant depression to receive a single dose of a proprietary, synthetic formulation of psilocybin at a dose of...

2023年9月7日 · A recent study in JAMA, the top medical journal in the US, found that psilocybin (the active ingredient in so-called “magic mushrooms”) could provide rapid relief. A large team of researchers...

It was found that every study significantly favoured the use of psilocybin in reducing depressive symptoms, with few side effects. This gives psilocybin an advantage over commonly prescribed selective serotonin reuptake inhibitors (SSRIs), which carry …

Improvements in depression were apparent within 8 days of psilocybin dosing, consistent with a rapid onset of action, and were maintained across the 6-week follow-up period, without attenuation of the effect, and with higher point prevalence rates of MADRS-defined response and remission than has been observed in recent psilocybin studies of TRD ...

2022年11月3日 · This study, which is by far the largest clinical trial on the use of psilocybin for treatment-resistant depression to date, demonstrated that a single 25 mg dose of psilocybin reduces the severity of participants’ symptoms in comparison to a 1 mg control dose.

2020年11月4日 · In 2016, Johns Hopkins Medicine researchers first reported that treatment with psilocybin under psychologically supported conditions significantly relieved existential anxiety and depression in people with a life-threatening cancer diagnosis.

In this review we focused on randomised trials that contained an unconfounded evaluation of psilocybin in adults with symptoms of depression, regardless of country and language of publication.

Psychopharmacological therapies with psychedelics, particularly those with psilocybin, are showing promising potential for the treatment of depression, among other conditions. Some of their benefits include a rapid and exponential improvement in depressive symptoms and an increased sense of well-being that can last for months after the ...

Additionally, the focus on depression as a clinical outcome also neglects the potential role that psilocybin therapy holds in the treatment of conditions that are prevalent in BIPOC communities such as anxiety and depression that emerges as a result of ethnic/racial trauma (Davis et al. 2021b; Williams et al. 2021), which may be diagnosed as ...