Recombinant High-Mobility Group Box 1 (rHMGB1) Promotes …
2021年8月2日 · These results indicate that rHMGB1 promotes NRF2 independent mitochondrial fusion via CXCR4/PSMB5 pathway-mediated Drp1 proteolysis. rHMGB1 may influence …
Recombinant High-Mobility Group Box 1 (rHMGB1) Promotes …
2021年8月2日 · Schematic depiction of rHMGB1-induced mitochondrial fusion and the underlying mechanism. rHMGB1 combines and activates the membrane receptor CXCR4, then …
Potential Protective and Therapeutic Roles of the Nrf2 Pathway in ...
Proteasome beta 5 (PSMB5), which can degrade many aberrant and denatured intracellular proteins as well as functional proteins, is mediated by the Nrf2-ARE pathway in many cell types.
1,4-dihydropyridine Derivatives Increase mRNA Expression of
2021年6月28日 · Proteasome gene expression is triggered by the nuclear respiratory factor 1 (Nrf1). This transcription factor is, in turn, regulated by the mammalian target of rapamycin …
Induction of 26S proteasome subunit PSMB5 by the
2006年7月14日 · Activation of the Psmb5 promoter through the Nrf2-ARE pathway following 3-MC incubation is demonstrating that this system can be regulated by environmental stimuli. …
The promoter of PSMB5 is activated by sulforaphane treatment or …
Murine PSMB5 promoter constructs (A) and luciferase activities derived from these truncated promoters following treatment with sulforaphane (10 M) or cotransfection of an Nrf2 …
PSMB5 Gene - GeneCards | PSB5 Protein | PSB5 Antibody
2024年12月25日 · PSMB5 (Proteasome 20S Subunit Beta 5) is a Protein Coding gene. Diseases associated with PSMB5 include Cystic Fibrosis and Parkinson's Disease. Among its related …
患者基因检测结果，我们发现6例（2.1%）患者在耐 药后出现了PSMB5基因突变，其中4例患者获得了 部分缓解（partial response，PR）疗效，2例患者疗 效为疾病稳定（stable …
Binding of Nrf2 to PSMB5 promoter in intact cells. (A) Chromatin ...
ARE-containing promoter regions from PSMB5 and the GSTA1 promoter were detected in Nrf2 immunoprecipitants obtained from sulforaphane-treated wild-type cells.
Ilexgenin A inhibits mitochondrial fission and promote Drp1 ... - PubMed
These results demonstrated that IA could promote PSMB5 expression in an Nrf2-dependent manner, resulting in the suppression of mitochondrial fission, and thus improve endothelial …
Review Trash Talk: Mammalian Proteasome Regulation at the ...
2021年2月1日 · Immunoproteasome expression can be increased by interferon regulatory factor 1 (IRF1) after its expression is upregulated by the interferon gamma (IFNγ)-induced Stat1 …
Induction of 26S proteasome subunit PSMB5 by the bifunctional …
2006年7月14日 · Collectively, these results indicate that expression of proteasome subunit PSMB5 is modulated by bifunctional enzyme inducers in a manner independent of the …
Recombinant High-Mobility Group Box 1 (rHMGB1) Promotes …
2021年8月3日 · These results indicate that rHMGB1 promotes NRF2 independent mitochondrial fusion via CXCR4/PSMB5 pathway-mediated Drp1 proteolysis. rHMGB1 may influence …
突变型PSMB5调节免疫微环境诱导非小细胞肺癌抗PD-1免疫治疗 …
下一项： 能量限制抑制肿瘤血管生成对低剂量化疗的增敏效果与机制研究. 突变型PSMB5调节免疫微环境诱导非小细胞肺癌抗PD-1免疫治疗耐药的机制研究（国科金青年科学基金项目）。
The promoter of PSMB5 is regulated by the Nrf2-ARE pathway. (A ...
(A) Luciferase activity driven by the proximal PSMB5 promoter ( Ϫ 1.1kb-luc) following treatment with antioxidants in wild-type and nrf2 -disrupted cells. BHT, butylhydroxytoluene; EQ,...
PSMB5 plays a dual role in cancer development and ... - PubMed
2017年11月1日 · Based on our bioinformatics analysis, we hypothesized that PSMB5 contained immunosuppressive and oncogenic characteristics. To study the effects of PSMB5 on the …
Molecular basis of bortezomib resistance: proteasome subunit β5 (PSMB5 ...
2008年9月15日 · Study of the molecular mechanism of bortezomib resistance in these cells revealed (1) an Ala49Thr mutation residing in a highly conserved bortezomib-binding pocket in …
PSMB5 Rabbit mAb - Selleck中国
psmb5参与抗原呈递和氧化应激，与b细胞、cd4+t细胞、cd8+t细胞、树突状细胞、巨噬细胞和中性粒细胞的丰度密切相关。psmb5可作为hcc诊断和预后的生物标志物。此外，psmb5在多种 …
Proteasome Subunits Differentially Control Myeloma Cell …
Depleting PSMB6 prevented splicing of the major catalytic subunits PSMB5, PSMB7, PSMB8, and PSMB10; however, PSMB6 engineered without splicing function or catalytic activity, also …
Psmb5 Mouse qPCR Primer Pair (NM_011186)
A ready-to-use mix for SYBR Green qPCR, containing ROX reference and suitable for all qPCR instruments without adjusting the concentration of ROX. 1 vial of lyophilized qSTAR qPCR …