
PTDSS1 Gene - GeneCards | PTSS1 Protein | PTSS1 Antibody
2024年12月25日 · PTDSS1 (Phosphatidylserine Synthase 1) is a Protein Coding gene. Diseases associated with PTDSS1 include Lenz-Majewski Hyperostotic Dwarfism and Osteopathia …
Phosphatidylserine synthase 1 - Wikipedia
Phosphatidylserine synthase 1 is a protein that in humans is encoded by the PTDSS1 gene. [5] The protein encoded by this gene catalyzes the formation of phosphatidylserine from either …
甘油磷脂的代谢及相关生理功能 - 知乎 - 知乎专栏
磷脂酰丝氨酸(PS)可通过PE或PC与丝氨酸的碱基交换生成,由磷脂酰丝氨酸合酶(PTDSS)催化。 PTDSS1对PC亲和力更高,而PTDSS2用于催化PE。 PS可被PISD催化脱羧生成PE,构 …
Phosphatidylserine synthesis controls oncogenic B cell receptor ...
2024年2月5日 · In a mouse xenograft model, PTDSS1 inhibition efficiently suppressed tumor growth and prolonged survival. Our findings suggest that PS synthesis may be a critical …
Molecular insights into human phosphatidylserine synthase 1 …
2024年10月3日 · In mammalian cells, two phosphatidylserine (PS) synthases drive PS synthesis. Gain-of-function mutations in the Ptdss1 gene lead to heightened PS production, causing Lenz …
PTDSS1 phosphatidylserine synthase 1 [ Homo sapiens (human) ]
2021年4月6日 · Knockdown of phosphatidylserine synthase 1 (PTDSS1) by siRNA inhibits the early stages of HIV-1 replication in 293T cells infected with VSV-G pseudotyped HIV-1 …
磷脂酰丝氨酸合酶 1(PTDSS1)基因 | MCE - MCE-生物活性 ...
磷脂酰丝氨酸定位于内质网的线粒体相关膜,在那里它起到结构作用和信号作用。 该基因的缺陷是导致 Lenz-Majewski 骨质增生性侏儒症的原因。 已发现该基因的两个转录本变体编码不同的 …
PTDSS1 phosphatidylserine synthase 1 [ (human)] - National …
We describe an adult phenotype and two novel PTDSS1 mutations. We suggest that LMS should be considered in the differential diagnosis of a newborn with CL. RYR2, PTDSS1 and AREG …
Phosphatidylserine Synthase PTDSS1 Shapes the Tumor Lipidome …
2022年4月15日 · PS was produced by phosphatidylserine synthase 1 (PTDSS1), and depletion of Ptdss1 from tumor cells in mice reduced ePS levels accompanied by stunted tumor growth …
磷脂酰丝氨酸合酶 PTDSS1 塑造肿瘤脂质组以维持促肿瘤炎 …
PS 由磷脂酰丝氨酸合酶 1 (PTDSS1) 产生,小鼠肿瘤细胞中 Ptdss1 的消耗降低了 ePS 水平,同时肿瘤生长受阻,肿瘤相关巨噬细胞 (TAM) 丰度降低。 Ptdss1缺陷的肿瘤细胞在凋亡过程中 …