PXB-mice have up to 95% human hepatocyte engraftment in the liver, and express stable blood levels of human albumin, a biomarker of humanization, over their life span. That means you …

Our PXB-mouse is the world’s most widely used humanized liver mouse model for drug development. With our stable and consistent production line, we rigorously select top-quality …

PXB-mice allow for unrivalled translational relevance in preclinical drug discovery and development projects, helping you to better predict the efficacy and toxicity of your drug …

PXB-mouse® is a cDNA-uPA/SCID chimeric mouse with humanized liver with more than 70% of the liver replaced with human hepatocytes. Immunodeficient mice are transplanted via splenic …

2020年1月8日 · We have succeeded in stable mass production of chimeric PXB-mice, whose liver is repopulated by human hepatocytes at a ratio of more than 70%, and we are providing these …

Recently, the chimeric mouse with humanized liver (PXB mice) became widely used as a humanized model in which human hepatocytes are transplanted. In the present study, we …

PhoenixBio Group is utilizing its proprietary platform technology of small animal model of chimeric mouse with highly humanized liver, the PXB-mouse®. The PXB-mouse ® and PXB-cells ® are …

2024年10月1日 · The ability of PXB-mouse with humanized liver to predict organic anion-transporting polypeptide 1B (OATP1B)-mediated drug-drug interactions (DDIs) in humans was …

We developed a chimeric mouse (PXB-mouse ®) in which mouse hepatocytes (m-heps) are largely replaced with transplanted h-heps expressing h-cytochrome P450 (CYP) enzymes [2, …

The PXB-Mouse® is the most commercially advanced and extensively published Mu/Hu Liver Chimeric model for drug development. The PXB-Mouse® is used extensively in liver disease …