2020年9月8日 · The present study was designed to assess the effect of intravenous (i.v.) injection and intramuscular (i.m.) injection of (pyr)apelin-13 on the inflammatory pain induced by the formalin test. The mechanistic basis for the underlying effect was explored by quantitative real-time polymerase chain reaction (RT-qPCR), western blot, and ELISA.

本研究的目的是调查健康麻醉大鼠注射超极化 （HP） [1-13C] 丙酮酸 （Pyr） 后脑乳酸 （Lac） 信号的来源。 具有血流敏化梯度的动态二维螺旋化学位移成像显示血管和脑 Pyr 均降低，而 Lac 对血流抑制水平没有显着依赖性。

2008年1月29日 · Pyruvate (Pyr) is an endogenous substrate enriched at a crossroad of the major energy-generating metabolic pathways in mammalian cells (1). Under most physiological conditions, the bulk of intracellular Pyr is generated endogenously by glycolysis of glucose or oxidation of lactate (Lac) (2).

2020年9月8日 · Intramuscular injection of (pyr)apelin-13 reduced licking/biting time during the second phase only at a dose of 20 mg/kg. The antinociception of i.v. (pyr)apelin-13 was antagonized by the apelin receptor (APJ, angiotensin II …

2013年6月10日 · Pyr 1 apelin13 reduces LPS-induced TNF-α release in hypothalamic microcultures. Intracerebroventricular (i.c.v.) injections of apelins have been shown to modulate the central control of cardiovascular function, as well as the homeostasis of fluid and salt balance, and to some extent also body core temperature.

TNF-α infusion-promoted neuroinflammation in the PVN and SFO in dams was abolished by PYR. Collectively, our data suggest that PYR improves PE-like symptoms in rat by dampening placental ischemia and TNF-α-promoted inflammation and pro-hypertensive activity in the PVN.

Hyperpolarized [1-13 C]pyruvate (Pyr) has been used to assess metabolism in healthy and diseased states, focusing on downstream labeling of lactate (Lac), bicarbonate (Bic), and alanine

Vulcan Forged PYR (PYR) 转换至 Injective (INJ) - PYR/INJ - CocoRate.com

Convert Vulcan Forged PYR(PYR) to Injective(INJ) with our cryptocurrency converter. Find other trending trade pairs on Coinbase.

2023年1月20日 · MEXC will list Injective (INJ) and Vulcan Forged (PYR) in the Innovation Zone and open trading for the INJ/USDT and PYR/USDT trading pair. The specific timeline is shown below: Deposit & Withdrawal: Opened; INJ/USDT Trading: 10:00 2023-01-20 (UTC) PYR/USDT Trading: 12:00 2023-01-20 (UTC)