
Should we treat pyrexia? And how do we do it? - Critical Care
2016年10月3日 · The concept of pyrexia as a protective physiological response to aid in host defence has been challenged with the awareness of the severe metabolic stress induced by pyrexia. The host response to pyrexia varies, however, according to the disease profile and severity and, as such, the management of pyrexia should differ; for example, temperature …
Pyrexia: aetiology in the ICU | Critical Care | Full Text - BioMed …
2016年9月1日 · Most episodes of pyrexia are due to infections, but incidence estimates of infectious and noninfectious aetiologies are limited by studies with small sample size and inconsistent reporting of noninfectious aetiologies. Pyrexia commonly triggers a full septic work-up, but on its own is a poor predictor of culture-positivity.
noninfectious pyrexia, is more commonly observed in patients with hyperthermia. Most episodes of pyrexia are due to infections, but incidence estimates of infectious and noninfectious aetiologies are limited by studies with small sample size and inconsistent reporting of noninfectious aetiologies. Pyrexia commonly triggers a full septic work-up,
The pathophysiological basis and consequences of fever
2016年7月14日 · The teleological benefit of pyrexia following brain injury is uncertain. Endocrine fever. Thyroid hormones are essential for regulation of energy metabolism. Hyperthyroidism is associated with hyperthermia; patients with thyroid storm have an average body temperature of 38.0 °C; temperatures above 41 °C have been reported . The mechanism of ...
2015年4月12日 · meaning simply ‘heat’, and pyrexia comes from the Greek ‘pyr’, meaning fire or fever. Some sources use the terms interchangeably, whereas others preserve ‘fever’ to mean a raised temperature caused by the action of thermoregula-tory pyrogens on the hypothalamus; for instance, in sepsis and inflammatory conditions [3].
Fever and hypothermia represent two populations of sepsis …
2021年10月21日 · Background Fever and hypothermia have been observed in septic patients. Their influence on prognosis is subject to ongoing debates. Methods We did a secondary analysis of a large clinical dataset from a quality improvement trial. A binary logistic regression model was calculated to assess the association of the thermal response with outcome and a multinomial …
The cost of pyrexia should be considered in several ways. Pyrexia has a metabolic cost such that cooling fe-brile ICU patients will reduce oxygen consumption by 10 % per °C [6]. Small studies in sedated patients dem-onstrated a significant reduction in VO 2 (the rate of oxy-gen consumption) and VCO 2 (the rate of carbon dioxide
Fever in sepsis: is it cool to be hot? - Critical Care
2014年2月13日 · Changes in body temperature are a characteristic feature of sepsis. The study by Kushimoto and colleagues in a recent issue of Critical Care demonstrates that hypothermia is a very important manifestation of infection associated with very high mortality. Combined with recent data suggesting that febrile patients with infections have the lowest mortality risk, the study …
Targeted temperature control following traumatic brain injury: …
2024年5月20日 · Aims and scope The aim of this panel was to develop consensus recommendations on targeted temperature control (TTC) in patients with severe traumatic brain injury (TBI) and in patients with moderate TBI who deteriorate and require admission to the intensive care unit for intracranial pressure (ICP) management. Methods A group of 18 …
Clinical review: Fever in septic ICU patients - friend or foe?
2011年6月7日 · In recent years, fever control in critically ill patients by medications and/or external cooling has gained widespread use, notably in patients suffering from neurological injuries. Nevertheless, such a strategy in septic patients is not supported by relevant data. Indeed, in response to sepsis, experimental and clinical studies argue that fever plays a key role in …