By utilizing zebrafish as a model organism, the Deng lab is uncovering exciting new genes and signaling mechanisms that govern the migration and activation of neutrophils, our bodies' powerhouse white blood cells.

Qing Deng Lab Our lab is interested in the mechanisms that regulate neutrophil migration and activation, more specifically their response to tissue injury and infection. The neutrophil is a hallmark of inflammation and neutrophilic inflammation, if not properly resolved, is the driving force behind a spectrum of human inflammatory diseases.

Deng Q, Huttenlocher A. Localized bacterial infection induces systemic activation of neutrophils through Cxcr2 signaling in zebrafish. J Leuk Biol , 2013 May; 93(5):761-9.

Qing Deng Lab » People People. Qing Deng. [email protected]. Principal Investigator. 765-494-0423 Tianqi Wang. [email protected]. Graduate student · Membrane potential and cell migration ... Deng Lab, Purdue University 915 W. State Street West Lafayette, IN 47907 Ph.

Deng Q, Sarris M, Bennin DA, Green JM, Herbomel P, Huttenlocher A. Localized bacterial infection induces systemic activation of neutrophils through Cxcr2 signaling in zebrafish.

Deng Q, Harvie EA, Huttenlocher A. Distinct signalling mechanisms mediate neutrophil attraction to bacterial infection and tissue injury. Cell Microbiol . 2012 Apr;14(4):517-28. doi: 10.1111/j.1462-

2018年3月8日 · Deng Lab - Neutrophil-specific knockout demonstrates a role for mitochondria in regulating neutrophil motility in zebrafish. 03-28-2018. Neutrophils are fast moving cells essential for host immune functions. Although they primarily rely on glycolysis for ATP, isolated primary human neutrophils depend on mitochondrial membrane potential for ...

Deng Q, Sarris M, Bennin DA, Green JM, Herbomel P, Huttenlocher A. Journal of leukocyte biology. 2013; 93(5):761-9. Low-volume toolbox for the discovery of immunosuppressive fungal secondary metabolites.

2024年7月25日 · Dr Qing Deng was promoted to full professor. Her research aims to enhance our understanding of neutrophil biology and develop targeted therapies for individuals suffering from debilitating diseases.

Qing Deng Lab » Research Research. We study neutrophil migration and the inflammation process using the zebrafish model. We are also interested in establishing novel infection models using zebrafish where pathogen-host interactions are made transparent. ... Deng Lab, Purdue University 915 W. State Street West Lafayette, IN 47907 Ph.