2021年2月1日 · Outcomes reported in the included RCT 8 were relapse rate, EDSS scores, quantification of optic nerve and spinal cord impairment (QOSI) scores, steroid reduction, AEs, …

2020年4月1日 · QOSI scores range from 0 to 69, with a high score associated with optic nerve and spinal cord impairment. As post-hoc analyses, we measured changes in AQP4 antibody …

2022年4月1日 · We performed a physical examination including vital signs and a neurological examination for EDSS and quantification of the optic nerve and spinal cord impairment (QOSI) …

Conversely, the authors report that the average change in total quantification of optic nerve and spinal cord impairment (QOSI) score was significantly higher in the placebo group. 37% of …

2022年5月16日 · Changes in EDSS and QOSI scores were compared between study groups and analysed using Student’s t test. • Rate of oral steroid reduction was analysed using Student’s t …

2021年7月1日 · Additionally, compared to baseline, rituximab reduced the quantification of nerve and spinal cord impairment (QOSI) scale (p= 0.03) [10] but had no significant effect on EDSS. …

The mean (SD) of EDSS was 3.5 (SD 2.2) at baseline and 3.5 (2.4) at the last visit, and the QOSI score changed from 10.0 (SD 8.3) at baseline to 9.5 (8.9) at the last visit, which was not ...

and spinal cord impairment (QOSI) scores at every visit of 4 weeks. Additionally, magnetic resonance imaging (MRI) of the brain and spinal cord (plain and gadolinium-enhancement), …

2020年12月16日 · In addition, the changes in the total quantification of nerve and spinal cord impairment (QOSI) scores were significantly higher in patients receiving RTX compared with …

2020年7月29日 · nerve and spinal cord impairment (QOSI) scores were signifi‑ cantly higher in patients receiving RTX compared with those receiving placebo (‑1.16 vs. 0.63; P=0.033).