发病率超过5%的主要肾癌（ renal cell carcinoma，RCC）亚型包括：透明细胞RCC (clear cell RCC，ccRCC) 、乳头状RCC (papillary RCC，pRCC) 和嫌色RCC (chromo phobe RCC，chRCC) 。

2024年2月15日 · Clear cell renal cell carcinoma (ccRCC) is a complex disease with remarkable immune and metabolic heterogeneity. Here we perform genomic, transcriptomic,...

2022年8月6日 · 肾细胞癌（RCC）的分类主要基于肿瘤的细胞学和结构特征以及免疫组化表达谱。 目前的世界卫生组织（WHO）分类由14个亚型RCC组成。 近年来，世界卫生组织认可的实体数量有所增加，并且随着新的或“新兴”亚型被考虑纳入而继续发展。 在本章中，我们概述了RCC不同亚型的关键特征，包括与遗传综合征相关的特征。 我们描述了未来可能被正式认可的2种“新兴”实体的特征，并简要讨论了新型生物标志物在RCC中的作用。 在过去25年中，肾脏恶性上皮肿瘤 …

Clear cell renal cell carcinoma, or ccRCC, is a type of kidney cancer. The kidneys are located on either side of the spine towards the lower back. The kidneys work by cleaning out waste products in the blood. Clear cell renal cell carcinoma is also called conventional renal cell carcinoma.

Renal cell carcinoma (RCC) is a heterogeneous group of cancers arising from renal tubular epithelial cells that encompasses 85% of all primary renal neoplasms 1, 2. The most common subtypes of RCC are clear cell RCC (ccRCC), papillary RCC, and chromophobe RCC 1. The remaining 15% of tumors of the kidney consist of transitional cell carcinoma (8 ...

6 天之前 · Renal cell carcinoma (RCC) constitutes 85% of kidney cancer and consists of 3 major subtypes: clear cell RCC (ccRCC, 80%), papillary RCC (pRCC, 15%), and chromophobe RCC (chRCC, 5%) . ccRCC is the ...

2025年2月8日 · Recent advances in genome analyses of ccRCC indicate that in ccRCC, tumor-initiating cells (TICs) and metastasis-initiating cells (MICs) are two distinct groups of progenitors. MICs result from various genetic changes during subclonal evolution, while TICs reside in the stem of the ccRCC phylogenetic tree of clonal development.

2 天之前 · Clear cell renal cell carcinoma (ccRCC), constituting approximately 70% of all adult renal cell carcinoma (RCC) cases, is the predominant histological subtype 1.Characterized by its aggressive and ...

4 天之前 · Clear cell renal cell carcinoma (ccRCC) is the predominant histological subtype of renal cell carcinoma (RCC), representing approximately 75% of all RCC cases, which is a prevalent urinary system malignancy characterized by a high metastasis rate and a dismal 5-year survival rate following metastasis [1, 2].In 2022, China and the United States recorded over 70,000 new ccRCC cases, with ...

1 天前 · Changes in the SMO gene were also found in ccRCC and other benign (non-AML or OCT) cases, while KDR c.889G > A mutation was found in 25.0% (13/52) of all cases, both p/ccRCC or benign. On average patients with RCC had 1.27 alterations (0–4 per patient), while patients with benign conditions on average had only 1.07 alterations per patient (0 ...