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2021年9月18日 · 滚环复制 (RCR, Rolling Circle Replication) 是一种单向核酸复制过程，可以快速合成多个拷贝的 DNA 或 RNA 环状分子，例如质粒、噬菌体的基因组和类病毒的环状 RNA 基因组。

2017年11月29日 · According to their biological roles, RCR initiator proteins are divided into three groups: Rep proteins (vegetative replication), Mob proteins (mobilization for conjugal transfer) and Tnp proteins (transposition).

Rolling-circle replication (RCR) is a mechanism adopted by certain plasmids, among other genetic elements, that represents one of the simplest initiation strategies, that is, the nicking by a replication initiator protein on one parental strand to generate the primer for leading-strand initiation and a single priming site for lagging-strand synt...

2017年11月30日 · In this review, we present a general overview of RCR and its impact in HGT. We focus on the molecular characteristics of RCR initiator proteins belonging to the HUH and Rep_trans protein families. Despite analogous mechanisms of action these are distinct groups of proteins with different catalytic domain structures.

2021年11月1日 · Rolling circle replication (RCR) is an isothermal nucleic acid amplification approach that holds great potential in biotechnology. RCR can serve as a powerful biosensing platform for the detection of various biomolecules in bioanalysis and diagnosis.

Rolling-circle replication (RCR) is a mechanism adopted by certain plasmids, among other genetic elements, that represents one of the simplest initiation strategies, that is, the nicking by a replication initiator protein on one parental strand to generate the primer for leading-strand initiation and a single priming site for lagging-strand ...

1992年7月11日 · An amino acid motif was identified that consists of the sequence HisHydrHisHydrHydrHydr (Hydr--bulky hydrophobic residue) and is conserved in two vast classes of proteins, one of which is involved in initiation and termination of rolling circle DNA replication, or RCR (Rep proteins), and the other i …

Rolling-circle replication (RCR) is a mechanism 6 adopted by certain plasmids, among other genetic elements, that represents one of the simplest 7 initiation strategies, that is, the nicking by a replication initiator protein on one parental strand to 8 generate the primer for leading-strand initiation and a single priming site for lagging...

An amino acid motif was identified that consists of the sequence HisHydrHisHydrHydrHydr (Hydr--bulky hydrophobic residue) and is conserved in two vast classes of proteins, one of which is involved in initiation and termination of rolling circle DNA replication, or RCR (Rep proteins), and the other in mobilization (conjugal transfer) of plasmid ...