2022年10月25日 · G4Atlas是一个全面的、面向全世界的、开放的、用户友好的rG4数据库，具有丰富的可交互与下载的资源。研究人员可以快速方便地锁定他们感兴趣的物种和或基因，获取详细的rG4信息和资源，也为进一步采用数据驱动的深度学习算法来研究rG4结构特征奠定了基础。

Provide a gene symbol or a Gencode gene / transcript id to search for RNA G-Quadruplexes (RG4), RG4BP-RG4 interactions and RG4BP binding sites into. Choose which RG4s to explore: experimentally determined, predictions or both.

RNA G-quadruplex (rG4) is a vital RNA tertiary structure motif that involves the base pairs on both Hoogsteen and Watson-Crick faces of guanines. rG4 is of great importance in the post-transcriptional regulation of gene expression. Experimental technologies have advanced to identify in vitro and in vivo rG4s across diverse transcriptomes.

RNA G-quadruplex (rG4) is a vital RNA tertiary structure motif that involves the base pairs on both Hoogsteen and Watson-Crick faces of guanines. rG4 is of great importance in the post-transcriptional regulations of gene expression.

2022年10月25日 · G4Atlas是一个全面的、面向全世界的、开放的、用户友好的rG4数据库，具有丰富的可交互与下载的资源。研究人员可以快速方便地锁定他们感兴趣的物种和或基因，获取详细的rG4信息和资源，也为进一步采用数据驱动的深度学习算法来研究rG4结构特征奠定了基础。

In this review, we will summarize the innovative high-throughput methods recently developed to detect rG4s on a transcriptome-wide scale, highlight the many novel and important functions of rG4 being discovered in vivo across the tree of life, and discuss the key biological questions to be addressed in the near future. INTRODUCTION

RNA G-quadruplexes (RG4s) are non-canonical, disease-associated post-transcriptional regulators of gene expression whose functions are driven by RNA-binding proteins (RBPs). Being able to explore transcriptome-wide RG4 formation and interaction with ...

2024年6月16日 · 预测rG4形成序列：使用生物信息学工具和算法来预测细菌基因组序列中可能形成rG4结构的RNA序列。这些工具通常基于G-四链体形成的序列特征，如富含鸟嘌呤（G）的重复序列。

2022年4月20日 · RNA G-quadruplex (rG4)-SELEX is a method that generates l-RNA aptamers to target an rG4 structure of interest, which can be applied to inhibit G-quadruplex-mediated...

2022年10月16日 · RNA G-quadruplex (rG4) is a vital RNA tertiary structure motif that involves the base pairs on both Hoogsteen and Watson-Crick faces of guanines. rG4 is of great...