Arginylglycylaspartic acid (RGD) is the most common peptide motif responsible for cell adhesion to the extracellular matrix (ECM), found in species ranging from Drosophila to humans.

Many adhesive proteins present in extracellular matrices and in the blood contain the tripeptide arginine-glycine-aspartic acid (RGD) as their cell recognition site. These proteins include …

RGD是一种由 Arg-Gly-Asp（精氨酸-甘氨酸-天冬氨酸）这三种氨基酸组成的序列多肽，广泛存在于细胞外基质（ECM）的蛋白中（如层粘蛋白、玻璃连接蛋白、纤维蛋白原和骨桥蛋白 …

In this article, we analyze the state-of-the-art knowledge on the roles of a subfamily of integrins, which require binding of the tripeptide motif Arg-Gly-Asp (RGD) for cell adhesion and signal …

The RGD (Arg-Gly-Asp) peptide is one of the most widely studied motifs. RGD is recognized by integrins that promote endocytosis of the polymer or particulate presenting the peptide. The …

The tripeptide Arg-Gly-Asp (RGD) was originally identified as the sequence within fibronectin that mediates cell attachment. The RGD motif has now been found in numerous other proteins and …

Proteins that contain the Arg-Gly-Asp (RGD) attachment site, together with the integrins that serve as receptors for them, constitute a major recognition system for cell adhesion. The RGD …

2024年7月22日 · The RGD peptide (less commonly known as Arginylglycylaspartic acid), whose name is derived from the single letter code of the core amino acids, Arginine-Glycine-Aspartic …

2007年6月1日 · The sequence arginine-glycine-aspartic acid (RGD) was identified as a general integrin-binding motif, but individual integrins are also specific for particular protein ligands. …

This paper reviews the main functions and advantages of RGD, describes the applications of RGD in imaging agents, drugs, gene delivery for tumor therapy, and highlights the role of RGD …