Arginylglycylaspartic acid (RGD) is the most common peptide motif responsible for cell adhesion to the extracellular matrix (ECM), found in species ranging from Drosophila to humans.

RGD是一种由 Arg-Gly-Asp （精氨酸-甘氨酸-天冬氨酸）这三种氨基酸组成的 序列多肽，广泛存在于 细胞外基质 （ECM）的蛋白中（如层粘蛋白、玻璃连接蛋白、纤维蛋白原和骨桥蛋白 …

RGD肽 （全称 精甘天冬氨酸肽，英語： RGD peptide 或 Arginylglycylaspartic acid）是由 L -精氨酸 、 甘氨酸 和 L -天冬氨酸 组成的 三肽 序列，存在于从 黑腹果蝇 到人类的许多动物的 细胞 …

2011年6月1日 · An exhaustive literature has established that RGD is highly effective at promoting the attachment of numerous cell types to a plethora of diverse materials. RGD is the principal …

An interaction between Sema7A and β-integrins was predicted from the presence of an arginine-glycine-aspartate amino acid sequence, known as an RGD-motif, in the Sema7A sema …

Many adhesive proteins present in extracellular matrices and in the blood contain the tripeptide arginine-glycine-aspartic acid (RGD) as their cell recognition site. These proteins include …

2024年2月4日 · RGD peptides can be utilized to specifically target cancer cells and the tumor vasculature by engaging with these integrins, improving drug delivery efficiency and …

2021年11月1日 · RGD integrins affect a multitude of disease-related proteins and molecular pathways. RGD integrins are key players in inflammation, leakage, angiogenesis and fibrosis. …

Arg-Gly-Asp (RGD) 是一种合成肽，对应于整合素 αVβ1、αVβ3、αVβ5、αVβ6、αVβ8、α8β1 和 α5β1 的细胞粘附序列。 它是放射性配体和肽模拟物的成分，已用于体内整合素表达和活性的研 …

2017年1月11日 · In this study, we evaluate a wide range of ligands for their binding affinity towards the RGD-binding integrins αvβ3, αvβ5, αvβ6, αvβ8, α5β1, αIIbβ3, using homogenous …