Accurate RNA 3D structure prediction using a language model …
2024年11月21日 · Here we present RhoFold+, an RNA language model-based deep learning method that accurately predicts 3D structures of single-chain RNAs from sequences.
GitHub - ml4bio/RNA-FM: Nature Methods: RNA foundation model …
This repository contains codes and pre-trained models for RNA foundation model (RNA-FM). RNA-FM outperforms all tested single-sequence RNA language models across a variety of structure prediction tasks as well as several function-related tasks.
An interpretable RNA foundation model for exploring functional RNA …
5 天之前 · Since RNA structure is the unique RNA feature incorporated in our PlantRNA-FM, we further identified the RNA secondary structure motifs important to translation through the model’s attention ...
Multi-purpose RNA language modelling with motif-aware
2024年5月13日 · Here we introduce RNAErnie, an RNA-focused pretrained model built upon the transformer architecture, employing two simple yet effective strategies.
Advances in RNA 3D Structure Modeling Using Experimental Data
In this review, we summarize the experiments that can be integrated into RNA structure modeling as well as the computational methods based on these experimental data. We also demonstrate how computational modeling can help the experimental determination of RNA structure.
Advances in the field of RNA 3D structure prediction and …
2024年9月24日 · Ribonucleic acids (RNAs) function in core cellular processes, including gene regulation, RNA splicing, and protein synthesis. Elucidating these processes requires knowledge of RNA structures and their interactions with various molecular partners.
3dRNA: Building RNA 3D structure with improved template library
2020年1月1日 · We firstly extract the base-pair information from the PDB-deposited RNA structure file, 1Y26.pdb. 3dRNA deals with RNA sequences with standard A, U, C and G and represents their secondary structures in ‘dot-bracket’ notation.
Geometric deep learning of RNA structure | Science - AAAS
2021年8月26日 · RNA molecules adopt three-dimensional structures that are critical to their function and of interest in drug discovery. Few RNA structures are known, however, and predicting them computationally has proven challenging.
RNA 3D Structure Prediction Using Coarse-Grained Models
2021年7月1日 · Here, we provide a review of CG models for modeling RNA 3D structures, compare the performance of the different models, and offer insights into potential future developments.
ModeRNA: a tool for comparative modeling of RNA 3D structure
2011年2月7日 · Here, we present ModeRNA, a software tool for comparative modeling of RNA 3D structures. As an input, ModeRNA requires a 3D structure of a template RNA molecule, and a sequence alignment between the target to be modeled and the template.