Retinal Pigment Epithelial (RPE) Tears, also known as RPE tears or rips, is a phenomenon first described in 1981 in which the RPE acutely tears from itself and retracts in an area of retina usually overlying a pigment epithelial detachment (PED) at the junction of detached RPE and flat RPE, leaving the underlying Bruch's membrane and choroid ...

Retinal pigment epithelium (RPE) is formed from a single layer of regular polygonal cells arranged at the outermost layer of the retina. The outer side of the RPE is connected to Bruch’s membrane and the choroid, while the inner side is connected to the outer segment of photoreceptor cells.

In a normal eye, fluorescein can not permeate through the endothelial cells of the retinal blood vessels nor can it pass through tight junctions in the retinal pigment epithelium (RPE). The yellow-green wavelength is also heavily absorbed by the RPE so the choroidal fluorescence is blocked.

Histopathologic studies showed an intact but attenuated retinal pigment epithelium with partial to complete loss of melanin granules, partial atrophy of the photoreceptor cells, and sclerosis of the choriocapillaris. • The clinical and histopathologic features of a solitary retinal pigment epithelial window defect are presented.

The term ‘congenital hypertrophy of retinal pigment epithelium’ or CHRPE was first coined by Buettner in 1975 to describe a solitary flat, pigmented, round lesion with sharply demarcated margins at the level of retinal pigment epithelium (RPE) (Fig. 1a, b) [2, 3].

The clinical and histopathologic features of a solitary retinal pigment epithelial window defect are presented. Fluorescein angiography disclosed an area with early choroidal fluorescence but no late staining. Histopathologic studies showed an intact but …

2017年5月15日 · Classic retinal pigment epithelium (RPE) tears in age-related macular degeneration (AMD) usually occur in patients with a fibrovascular pigment epithelium detachment. In respective cases a RPE tear may occur spontaneously, after administration of intravitreal anti- VEGF, or after photodynamic therapy [ 1 , 2 , 3 , 4 ].

Retinal pigment epithelial cells (RPE) constitute a simple layer of cuboidal cells that are strategically situated behind the photoreceptor (PR) cells. The inconspicuousness of this monolayer contrasts sharply with its importance [1].

2012年12月14日 · Fundus autofluorescence (FAF) displays lipofuscin at the level of the retinal pigment epithelium (RPE), which is considered a useful method to detect early RPE alternations. FAF has demonstrated specific RPE abnormalities in various fundus disorders such as age-related macular degeneration, Stargardt disease, retinitis pigmentosa (RP), and ...

Characteristics such as subretinal pigment epithelium (RPE) ring-like lesion, en face OCT-complex RPE elevation, and sharp-peaked pigment epithelial detachment provide high...