Central sensitization and LTP: do pain and memory share similar mechanisms? Cytokine mechanisms of central sensitization: distinct and overlapping role of interleukin-1β, interleukin-6, and tumor...

As the Director of the Center for Translational Pain Medicine (CTPM) and a highly cited researcher (Cross Field, Clarivate), I have both administrative and scientific leadership for successful completion of many research projects. Xu, Jing, Zihan Yan, Sangsu Bang, Dmitry Velmeshev, and Ru-Rong Ji.

2025年2月13日，美国杜克大学 Ru-Rong Ji 教授团队在神经科学期刊 Neuron 杂志发表了题为： GPR37L1 identifies spinal cord astrocytes and protects neuropathic pain after nerve injury 的研究论文。 该研究鉴定了脊髓星形胶质细胞高度特异的G 蛋白偶联受体 （GPCR） 分子-GPR37L1，并且星形胶质细胞GPR37L1 通过谷氨酸转运蛋白-1 （GLT-1） 调节脊髓背角的兴奋性突触传递，进而缓解神经损伤引起的神经性疼痛。 此发现为慢性疼痛药物开发提供的新的靶点。

Ru-Rong Ji, PhD, is the chief of pain research within Duke Anesthesiology, director of the Center for Translational Pain Medicine, and a professor of anesthesiology and neurobiology. As director of the Sensory Plasticity and Pain Research Laboratory at Duke, his research focuses on molecular and cellular mechanisms of chronic pain, such as ...

2024年12月3日 · Distinct roles of mTORC2 in excitatory and inhibitory neurons in inflammatory and neuropathic pain. Pre-Clinical Assessment of Bupivacaine-Loaded Poly (ester urea) Thin Films for Controlled Drug Release and Effective Pain Management After Surgery.

We believe that tackling the mechanisms of pain induction and resolution will lead to the development of novel therapeutics for preventing and treating chronic pain. The Ji lab is always recruiting talented postdoctoral fellows, visiting scholars, graduate students, and …

We investigate the molecular and cellular mechanisms underlying the induction, maintenance, and resolution of persistent pain. We focus on spinal cord synaptic transmission and the role of glial cells. We use a range of molecular, cellular, electrophysiological, and behavioral approaches in transgenic mice.

Ru-Rong JI, Professor (Full) and Chief of Pain Research | Cited by 39,805 | of Duke University Medical Center, Durham (DUMC) | Read 314 publications | Contact Ru-Rong JI

2020 25th International Conference on Engineering of Complex Computer …

Ru Ji, Yang He, Zuotai Zhang, Lili Liu and Xidong Wang. The effect of expanded perlite on the performance of the lightweight wa...