A sixth sense for Rab5 | Nature Cell Biology
2005年6月1日 · Rab5 is one of the more intensely studied members of the large and diverse family of Rab GTPases 1. Functional studies indicate that it is a key regulator of early …
The Emerging Role of Rab5 in Membrane Receptor Trafficking and ...
2020年2月11日 · Early endosome marker Rab5 GTPase, a key member of the Rab family, plays a crucial role in endocytosis and membrane transport. The activated-state Rab5 recruits its …
The Rab5 Effector Rabankyrin-5 Regulates and Coordinates
2004年8月24日 · Here we discovered a novel PI (3)P-binding Rab5 effector, Rabankyrin-5, which localises to early endosomes and stimulates their fusion activity. In addition to early …
华中科大史岸冰团队鉴定功能偶联的早期内吞体亚群上RAB-5/Rab5 …
2020年9月23日 · 小GTP酶 (small GTPase) Rab5/RAB-5定位于早期内吞体，募集效应因子以调控包括内吞循环运输在内的多类型生物学过程[1-3]，例如Rab5效应蛋白Rabenosyn-5与Rab4、 …
A role for Rab5 in structuring the endoplasmic reticulum
2007年7月2日 · Perturbation of endocytosis by other means did not affect ER structure; the role of RAB-5 in ER morphology is thus independent of its well-studied requirement for endocytosis. …
RAB5B Gene - GeneCards | RAB5B Protein | RAB5B Antibody
2024年12月25日 · RAB5B (RAB5B, Member RAS Oncogene Family) is a Protein Coding gene. Diseases associated with RAB5B include Amyotrophic Lateral Sclerosis 1 and …
Caenorhabditis elegans RME-6 is a novel regulator of RAB-5 at …
2005年5月15日 · Consistent with the known catalytic function of Vps9 domains in Rab5 GDP/GTP exchange, we found that RME-6 binds specifically to Caenorhabditis elegans RAB-5 in the …
172755 - Gene Resultrab-5 small monomeric GTPase []
RAB-5 promotes C. elegans embryonic polarity in both dynamin-dependent and -independent manners, by controlling PAR-6 localization. RAB-5 and RAB-11 are required for plasma …
Rab5-mediated endosome formation is regulated at the
Here we show instead that endocytosis is dispensable and post-Golgi vesicle transport is crucial for the formation of endosomes and the subsequent endolysosomal traffic regulated by yeast …
RAB5A - Wikipedia
RAB5A localizes to early endosomes where it is involved in the recruitment of RAB7A and the maturation of these compartments to early endosomes. [7] . It drives the maturation of …