Ran (RAs-related Nuclear protein) also known as GTP-binding nuclear protein Ran is a protein that in humans is encoded by the RAN gene. Ran is a small 25 kDa protein that is involved in …

NPC含有有三个大的环状结构，即细胞质环（外环），中央辐条环（central spoke ring，也称为膜环）和核质环（内环），它们构成稳定的轮状支架，包围着中央转运体（central transporter） …

2024年2月1日 · We propose that despite the presence of centrosomes, the chromosome-derived Ran-GTP pathway has essential roles in functional spindle assembly in large, rapidly dividing …

Ran-GTP-binding proteins act as nuclear import and export receptors. Import receptors bind their cargo in the cytosol, where Ran-GTP concentrations are low, and dissociate in the nucleus. …

2020年5月26日 · Ran (Ras-related nuclear protein) GTPase is a member of the Ras superfamily. Like all the GTPases, Ran cycles between an active (GTP-bound) and inactive (GDP-bound) …

2024年12月25日 · RAN (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the …

2002年7月1日 · The small GTPase Ran is a key regulator of nucleocytoplasmic transport during interphase. The asymmetric distribution of the GTP-bound form of Ran across the nuclear …

Ran是一种大量分布于细胞核内的GTP酶, 是Ras类原癌基因大家族中的一员. Ran的功能多种多样, 有许多证据表明Ran及其结合蛋白参与调控细胞周期中的多个过程.

RAN (ras-related nuclear protein) is a small GTP binding protein belonging to the Ras superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. …

2016年1月10日 · In its GTP bound form, Ran (RanGTP) interacts with karyopherin-β proteins with high affinity, while it dissociates in its GDP bound form (RanGDP). RanGTP binding to …