Ethanol extract of Hedyotis leschenaultiana whole plant was evaluated for Oral Glucose Tolerance Test (OGTT) in normal and alloxan induced diabetic rats. Blood glucose concentration was evaluated at 0, 30, 60, 90 and 120 minutes after treatment in both cases.

We developed four different diabetic animal models. In each model, rats were treated with metformin, dapagliflozin, and insulin respectively for 1 week. OGTTs were performed after 7 days of the drug treatment. The acute blood glucose changes induced by one-time treatment of drugs were also compared.

In this review, we describe the central principles of the metabolic tests available in order to study glucose and insulin homeostasis in mice, focusing on the most widely used – the glucose and insulin tolerance tests.

2012年12月12日 · An OGTT is used clinically to diagnose impaired glucose tolerance and as a standardized test of carbohydrate metabolism and insulin secretion. The test is based on oral administration of glucose and subsequently following plasma glucose and insulin levels over time.

2023年10月19日 · Nile rats labeled A to J are ordered on the basis of area under the curve of glucose levels during OGTT (OGTT glucAUC) (Fig. 1c) and show a range of glucose tolerance evenly distributed...

The Oral Glucose Tolerance Test (oGTT) measures the clearance of an orally administered glucose bolus from the body. It is used to detect disturbances in glucose metabolism that can be linked to human conditions such as diabetes or metabolic syndrome. Animals are fasted for approximately 16 to.

The aim of this study is to investigate the hypoglycemic effects of petroleum ether, chloroform and ethyl acetate fractions isolated from ethanolic extracts of Coccinia cordifolia and Catharanthus roseus on normal control and orally glucose-induced …

The summary of techniques used for OGTT (in vivo), pancreatic islets isolation and glucose stimulated insulin secretion (GSIS) ( ex vivo ) procedures in rats. OGTT measures the blood glucose and insulin at different time points.

Treating ZDF rats with anti-diabetic drugs significantly reduced blood glucose levels during the OGTT. In addition, the blood glucose AUC was smaller in treated diabetic animals compared with...

SDT rats are an inbred strain of Sprague-Dawley rat that spontaneously develop hyperglycemia, glucose intolerance, and deficient insulin production owing to β-cell degeneration.