2019年6月24日 · An accurate knowledge of tissue optical properties (absorption coefficients, μa, and reduced scattering coefficients, μs’) is critical for precise modeling of light propagation in biological ...

In order to estimate multispectral images of the absorption and scattering properties in the cerebral cortex of in vivo rat brain, we investigated spectral reflectance images estimated by the Wiener estimation method using a digital RGB camera. A Monte Carlo simulation-based multiple regression anal …

2023年6月6日 · To address the insufficiency in reported peripheral nerve optical properties, the primary goal of this study was to determine the absorption and reduced scattering coefficients of nerve and surrounding tissue in both rats and humans for …

Our study has aimed to measure absorption, scattering, reduced scattering coefficients, and scattering anisotropy factor of brain tissues in healthy rats and rats with a C6 model glioblastoma (7, 10, and 30 days) in a wide spectral range from 350 to1800 nm.

2014年4月30日 · For the first time, we detected optical changes elicited by seizure activity in pentylenetetrazol (PTZ)-treated rats (n = 6) versus saline controls (n = 2) over a 30 min recording session using a novel time-series analysis of scattering images obtained non-invasively with a real-time multispectral diffuse optical tomography (DOT) system.

As discussed, rat cortex is thicker relative to mouse cortex and this increased depth increases light scattering, decreases SNR, and prevents optical access to deep layers.

2013年8月1日 · In this study, we simultaneously investigated changes in HbO, HbR, FAD, cytochrome c, cytochrome aa3 and light scattering during CSD by applying multi-spectral OIS imaging at 450, 470, 500, 530, 550, 570, 600, 630, and 650 nm in the rat brain.

2014年1月8日 · In the total of 24 rats examined, drastic scattering change accompanying EEG suppression, which indicated the occurrence of spreading depression, was observed for 18 rats; prolonged hypoxemia was observed in 15 (83.3%) of those 18 rats and heme aa 3 reduction was indicated in 14 (77.8%) of those 18 rats, showing a strong correlation between ...

Diffuse reflectance spectroscopy (DRS) has been extensively used for characterization of biological tissues as a noninvasive optical technique to evaluate the optical properties of tissue. We investigated a method for evaluating the reduced scattering coefficient μ (s)', the absorption coefficient μ ( …

Simultaneous detection of hemodynamics, mitochondrial metabolism and light scattering changes during cortical spreading depression in rats based on multi-spectral optical imaging.