A retrovirus is a type of virus that inserts a DNA copy of its RNA genome into the DNA of a host cell that it invades, thus changing the genome of that cell. [2] . After invading a host cell's cytoplasm, the virus uses its own reverse transcriptase enzyme to produce DNA from its RNA genome, the reverse of the usual pattern, thus retro (backward).

2024年12月31日 · retrovirus, any of a group of viruses that belong to the family Retroviridae and that characteristically carry their genetic blueprint in the form of ribonucleic acid (RNA). Retroviruses are named for an enzyme known as reverse transcriptase, which was discovered independently in 1971 by American virologists Howard Temin and David Baltimore.

2023年7月16日 · A retrovirus is a virus that works by converting its own RNA into DNA once it is in a host cell. It then integrates this DNA into the DNA of the host cell, allowing the virus to...

2023年5月22日 · What Is a Retrovirus and How Does It Work? A retrovirus is a type of RNA virus. RNA viruses have genes encoded in RNA instead of DNA. Like other viruses, retroviruses need to use the cellular machinery of the organisms they infect to make copies of themselves. Infection by a retrovirus, however, requires an additional step.

2019年3月1日 · Retroviruses are a type of virus in the viral family called Retroviridae. They use RNA as their genetic material and are named for a special enzyme that’s a vital part of their life cycle — reverse...

5 天之前 · A retrovirus is a virus that uses RNA as its genomic material. Upon infection with a retrovirus, a cell converts the retroviral RNA into DNA, which in turn is inserted into the DNA of the host cell. The cell then produces more retroviruses, which infect other cells.

Retroviruses comprise a large and diverse family of enveloped RNA viruses defined by common taxonomic denominators that include structure, composition, and replicative properties (Coffin 1992a, b, 1996). The virions are 80–100 nm in diameter, and their outer lipid envelope incorporates and displays the viral glycoproteins (Fig. 1).

Similar to other vertebrate animals, humans possess retroviruses that exist in two forms: as normal genetic elements in their chromosomal DNA (endogenous retroviruses) and as horizontally-transmitted infectious RNA-containing viruses which are transmitted from human-to-human (exogenous retroviruses, e.g. HIV and human T cell leukemia virus, HTLV).

Retroviruses are associated with a wide variety of diseases including an array of malignancies, immunodeficiencies, and neurologic disorders. Syndromes as seemingly diverse as arthritis, osteopetrosis, and anemia can all result from retroviral infection.

2023年2月1日 · Retroviruses are important human and animal pathogens. Steps of retrovirus life cycle are described along with recent significant updates. Current understanding of retroviral genomic RNA packaging is described in detail. How spliced RNAs are excluded and unspliced RNAs marked for translation are discussed.