Revita is an outpatient endoscopic procedure designed to durably modify duodenal dysfunction via hydrothermal ablation in order to restore metabolic health. Evidence suggests that Revita could potentially provide durable weight maintenance for patients living with obesity.

2016年8月12日 · Duodenal mucosal resurfacing (DMR) is a novel, minimally invasive, catheter-based upper endoscopic procedure involving hydrothermal ablation of the duodenal mucosa and subsequent mucosal healing. DMR could recapitulate, less invasively, some of the mechanisms of action of gastrointestinal bypass surgery.

2020年6月3日 · 正在研究 Revita ®系统，以评估 DMR 与 Sham 在改善胰岛素治疗控制不佳的 2 型糖尿病患者的血糖、肝脏和心血管终点方面的疗效。 本研究的目的是证明与假手术相比，使用 Rev...。

REVITA-2, a double-blind, superiority randomised controlled trial, investigates safety and efficacy of DMR using the single catheter Revita system (Revita DMR (catheter and system)), on glycaemic control and liver fat content in type 2 diabetes (T2D).

Aims: Duodenal mucosal resurfacing (DMR) is an endoscopic procedure developed to improve metabolic parameters and restore insulin sensitivity in patients with diabetes. Here we report long-term DMR safety and efficacy from the REVITA-1 study.

REVITA-2, a double- blind, superiority randomised controlled trial, investigates safety and eficacy of DMR using the single catheter Revita system (Revita DMR (catheter and system)), on glycaemic control and liver fat content in type 2 diabetes (T2D).

2020年3月30日 · Patients with poorly controlled type 2 diabetes who underwent a novel, minimally invasive, endoscopic procedure called Revita® duodenal mucosal resurfacing (DMR) had significantly improved blood glucose (sugar) levels, liver insulin sensitivity, and other metabolic measures three months later, according to new data from the REVITA-2 study.

REVITA-1 was a prospective, single-arm, open-label, multicenter study of DMR feasibility, safety, and efficacy in patients with type 2 diabetes (hemoglobin A1c [HbA1c] of 7.5–10.0% (58–86 mmol/mol)) on oral medication.

2021年4月27日 · Revita DMR (duodenal mucosal resurfacing) is a first-in-class intervention targeting the role of the intestine in metabolic disease. It is an outpatient procedural therapy...

2019年11月11日 · • Revita® DMR catheter is designed to perform submucosal lift and hydrothermal ablation of hyperplastic duodenal mucosa, promote healthy epithelial regrowth within 12 weeks, and reduce insulin resistance and hyperinsulinemia 1,2