In this review, we focus on the biochemical properties of the RGG motif, its molecular interactions with RNAs and proteins, and roles of the posttranslational modification in modulating their interactions.

通过精氨酸和甘氨酸的独特组合，结合由重复的二肽、三肽和多肽基序赋予的多样性分子识别，使 RGG 基序蛋白能够与广泛的蛋白质相互作用，从而实现多功能、特异性但适应性强的分子相互作用和核酸。 此外，基序中精氨酸的翻译后修饰扩展了 RGG 蛋白的微调调节能力。 在这篇综述中，我们重点关注 RGG 基序的生化特性、它与 RNA 和蛋白质的分子相互作用，以及翻译后修饰在调节它们相互作用中的作用。

2018年11月2日 · RGG/RG regions are disordered protein regions with multiple RGG/RG repeats. They bind RNA and DNA likely via weak multivalent interactions. RGG/RG regions undergo LLPS with or without RNA. RNA binding and LLPS are modulated by methylation of arginines in RGG/RG motifs.

4 天之前 · RNA binding proteins (RBPs) are enriched in phase separated biomolecular assemblies across cell types. These RBPs often harbor arginine–glycine rich RGG motifs, which can drive phase separation ...

2013年6月6日 · Motifs rich in arginines and glycines were recognized several decades ago to play functional roles and were termed glycine-arginine-rich (GAR) domains and/or RGG boxes. We review here the evolving functions of the RGG box along with several sequence variations that we collectively term the RGG/RG mo …

The RGG box is required for several functions of FMRP critical to its role in controlling local mRNA translation to effect activity-dependent synaptic plasticity in neurons, providing a critical link between RNA binding by this domain and protein function in vivo.

The SRL_GLOBAL_PLANNER package provides an implementation of the sampling based motion planners (RRT, RGG, RRT*, Theta*-RRT) as global planner plugin for Move-base, a ROS framework Resources Readme

rggX is a random geometric graph with 2^X vertices. Each vertex is a random point in the unit square and edges connect vertices whose Euclidean distance is below 0.55 ln n/n. This threshold was choosen in order to ensure that the graph is almost connected. Reference: M. Holtgrewe, P. Sanders, and C. Schulz.

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