2013年6月6日 · Motifs rich in arginines and glycines were recognized several decades ago to play functional roles and were termed glycine-arginine-rich (GAR) domains and/or RGG boxes. We review here the evolving functions of the RGG box along with several sequence variations that we collectively term the RGG/RG motif.

In this review, we focus on the biochemical properties of the RGG motif, its molecular interactions with RNAs and proteins, and roles of the posttranslational modification in modulating their interactions.

通过精氨酸和甘氨酸的独特组合，结合由重复的二肽、三肽和多肽基序赋予的多样性分子识别，使 RGG 基序蛋白能够与广泛的蛋白质相互作用，从而实现多功能、特异性但适应性强的分子相互作用和核酸。

2023年12月14日 · 研究表明，CHG甲基化可能与CpG岛的甲基化一样重要，但其在基因表达调控中的作用可能更为复杂。 CHH： CHH模式 在DNA甲基化中也存在，但与CpG岛相比，它通常出现在基因组的其他区域，特别是在增强子区域。

2020年9月10日 · Regulator gene of glucosyltransferase (Rgg) family proteins, such as Rgg2 and Rgg3, have emerged as primary quorum-sensing regulated transcription factors in Streptococcus species, controlling virulence, antimicrobial resistance, and biofilm formation.

2018年11月2日 · RGG/RG motifs are RNA binding segments found in many proteins that can partition into membraneless organelles. They occur in the context of low-complexity disordered regions and often in multiple copies.

In this review, we focus on the biochemical properties of the RGG motif, its molecular interactions with RNAs and proteins, and roles of the posttrans-lational modification in modulating their interactions.

2015年10月5日 · Genes were fractioned into groups by their expression level in leaves and each genic region was divided into three regions: 2 kb upstream, gene body, and 2 kb downstream regions. Reductions in CG and CHG methylation were observed in all three regions in asDDM1 (Figure 1 C, top and middle).

Motifs rich in arginines and glycines were recognized several decades ago to play functional roles and were termed glycine-arginine-rich (GAR) domains and/or RGG boxes. We review here the evolving functions of the RGG box along with several sequence variations that we collectively term the RGG/RG motif.

2013年6月6日 · Motifs rich in arginines and glycines were recognized several decades ago to play functional roles and were termed glycine-arginine-rich (GAR) domains and/or RGG boxes. We review here the evolving functions of the RGG box along with several sequence variations that we collectively term the RGG/RG motif.