A GRF–GIF chimeric protein improves the regeneration ... - Nature
2020年10月12日 · Here, we show that expression of a fusion protein combining wheat GROWTH-REGULATING FACTOR 4 (GRF4) and its cofactor GRF-INTERACTING FACTOR 1 (GIF1) …
Journal of Integrative Plant Biology - Wiley Online Library
2021年12月4日 · By combining rGRF-GIF with the CRISPR/Cas9 system, we were able to efficiently edit both tested genes individually and simultaneously in watermelon. We also used …
MicroRNA miR396, GRF transcription factors and GIF co …
2020年2月1日 · Consequently, mutations in the miR396-binding site of GRFs, which dampen the repression by the miRNA (usually called rGRF mutations, because they confer resistance to …
Effect of rGRF on exocrine pancreatic secretion of the rat in vivo
All three peptides stimulated pancreatic secretion. rGRF induced a slight water and electrolyte secretion, with an efficacy about ten times smaller than secretin, and a potency about thirty …
Rat growth hormone-releasing factor stimulates cyclic GMP
The effects of rat growth hormone releasing factor (rGRF) on somatostatin (SRIF) secretion, cyclic nucleotide production and phosphatidylinositol metabolism were investigated in the median …
Growth-Regulating Factors, A Transcription Factor Family …
2016年1月1日 · Numerous regulatory networks have been implicated in the establishment and maintenance of meristems and in promoting cell proliferation of developing organ primordia, …
Rat hypothalamic GRF elicits its biologic action in GH3 cells by ...
1985年3月29日 · Rat hypothalamic GRF, (rGRF) is 7 to 10 fold more active than human hypothalamic GRF (hGRF). VIP, a peptide which is structurally homologous to GRF, …
Biological roles and an evolutionary sketch of the GRF-GIF ...
GROWTH-REGULATING FACTORs (GRFs) are sequence-specific DNA-binding transcription factors that regulate various aspects of plant growth and development. GRF proteins interact …
Differential activation of type I and type II 3',5'-cyclic ... - PubMed
Rat GH-releasing factor (rGRF) stimulated GH release and intracellular cAMP accumulation in cultured rat anterior pituitary cells with EC50 values of approximately 10 and 150 pm, …
Binding sites for growth hormone releasing factor on rat …
Growth hormone releasing factors (GRFs) have been isolated from human pancreatic tumours (hGRF) 1–3 and rat hypothalamus (rhGRF) 4. The response to GRF at the pituitary level can be...