Receptor-interacting serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the RIPK2 gene. [5] [6] [7] This gene encodes a member of the receptor-interacting protein …

2024年12月25日 · RIPK2 (Receptor Interacting Serine/Threonine Kinase 2) is a Protein Coding gene. Diseases associated with RIPK2 include Crohn's Disease and Leprosy. Among its …

Receptor-interacting protein kinase 2 (RIPK2) is a downstream signaling molecule of nucleotide-binding oligomerization domain-containing proteins 1 and 2 (NOD1/2) and plays a cru-cial role …

2023年11月5日 · RIPK2 is an upstream regulator of stress-induced caspase-1 activation, which is essential for neuronal death induced by overexpression of RIPK2 [29]. Therefore, RIPK2 is …

2022年2月3日 · Here we show receptor-interacting protein kinase 2 (RIPK2) is a clinically actionable target for inhibiting PC metastasis. RIPK2 is amplified/gained in ~65% of lethal …

2023年10月19日 · 受体相互作用丝氨酸/苏氨酸蛋白激酶 2 (ripk2) 是一种下游信号分子，对于激活多种先天免疫受体（包括 nod 样受体（nod1 和 nod2））至关重要。 NOD1/2 对病原体相关 …

2023年11月5日 · The present study reviews the molecule structure and biological functions of RIPK2, and its correlation between human diseases. In addition, we focus on the structure …

2024年2月8日 · Our data showed that receptor-interacting protein kinase 2 (RIPK2) is a crucial driver of immune evasion of cytotoxic T-cell killing and that genetic or pharmacologic targeting …

该研究应用体内CRISPR筛选确定RIPK2是免疫逃避的关键驱动因素，并通过 新格元 GEXSCOPE® 单细胞转录组测序 (scRNA-Seq)技术 发现CD8+T细胞是PDAC肿瘤免疫微环境 …

2023年9月30日 · Receptor-interacting protein kinase 2 (RIPK2) is a serine/threonine kinase whose activity propagates inflammatory signaling through its association with pattern …