RodZ是跨膜蛋白，与其他蛋白质（例如MreB-肌动蛋白和肽聚糖合成酶（例如PBP2））形成称为Rod复合物的超分子复合物。 rodZ基因的缺失将细胞形状从杆状变为圆形或卵形。

2009年1月27日 · The molecular basis of bacterial cell morphogenesis remains largely an open question. Here we discover a morphogenic protein, RodZ, which is widely conserved across the bacterial kingdom. In Caulob...

2018年7月18日 · Unlike the membrane-bound periplasmic truncations (RodZ 1–155 and RodZ 1–142), a small truncation in the RodZ cytoplasmic domain (RodZ 59–337) shows a clear change in MreB curvature ...

2018年3月29日 · We identify MreB mutants that alter the bending properties of MreB filaments in molecular dynamics simulations similar to RodZ binding, and show that these mutants rescue rod-like shape in the ...

lobactercrescentus, RodZ is essential for viability and is involved in all aspects of this organism’s complex morphology. Depletion or over-production of RodZ results in grossly misshapen cells with stalk defects. RodZ exhibits a localization pattern during the cell cycle corresponding to sites of active peptidoglycan synthesis. The

2009年2月4日 · The protein, RodZ, is required for assembly of the actin cytoskeleton MreB that controls cell wall synthesis and cell shape. It is not yet understood how bacteria determine their shape. Almost all bacteria are surrounded by a giant cell wall polymer called peptidoglycan that gives shape to the cells and is an important target of antibiotics.

Abstract: RodZ is required for determination of cell shape in rod-shaped bacterium, such as Escherichia coli. RodZ is a transmembrane protein and forms a supramolecular complex called the Rod complex with other proteins, such as MreB-actin and peptidoglycan synthesis enzymes (for e.g., PBP2).

2018年3月29日 · 因此，大肠杆菌可以通过差异地调节RodZ和MreB来改变细胞壁插入的模式，从而控制其形状和尺寸，从而突出了细胞骨架分子生物物理学的丰富调控格局。

The molecular basis of bacterial cell morphogenesis remains largely an open question. Here we discover a morphogenic protein, RodZ, which is widely conserved across the bacterial kingdom. In Caulobacter crescentus, RodZ is essential for viability ...

2019年11月7日 · RodZ is a transmembrane protein and forms a supramolecular complex called the Rod complex with other proteins, such as MreB-actin and peptidoglycan synthesis enzymes (for e.g., PBP2). Deletion of the rodZ gene changes the cell shape from rod to round or ovoid.