2024年1月1日 · Here, we review the emerging role of cysteine in bacterial resistance to ROS with a link to broader elements of bacterial lifestyle closely associated with cysteine-mediated …

2021年9月16日 · ROS, in particular hydrogen peroxide (H 2 O 2), are able to reversibly oxidize critical, redox-sensitive cysteine residues on target proteins. These oxidative post-translational …

2018年4月20日 · Reactive oxygen species (ROS) are increasingly recognised as important signalling molecules through oxidation of protein cysteine residues. Comprehensive …

2013年3月20日 · Reactive oxygen, nitrogen, and sulfur species, referred to as ROS, RNS, and RSS, respectively, are produced during normal cell function and in response to various stimuli. …

2014年5月19日 · Elevated ROS oxidizes redox-sensitive cysteine residues on KEAP1, resulting in dissociation of KEAP1 from NRF2. Subsequently, NRF2 translocates to the nucleus, …

2021年2月25日 · H 2 O 2 directed thiol-based modification of cysteine residues in target proteins represents a chief mechanism of ROS mediated biological effects in redox regulation 24,25,26.

2012年1月27日 · Several proteins have been shown to function as effectors for ROS, which are sensitively and reversibly oxidized by ROS. Such ROS-effector proteins commonly possess a …

We present here, a review of relevant ROS biology, possible chemical reactions of Cys residues and details of the proteomic strategies employed for rapid, efficient and sensitive identification …

2023年4月25日 · Together, these methods identified the mitochondrial cysteines that were sensitive to endogenous and exogenous ROS, including several previously known redox …

Elevated ROS oxidizes redox sensitive cysteine residues on KEAP1 resulting in dissociation of KEAP1 from NRF2. Subsequently, NRF2 translocates to the nucleus, heterodimerizes with …