ROS-ERK Pathway as Dual Mediators of Cellular Injury and
2021年3月1日 · ERK, an extracellular signal-regulated protein kinase, is involved in various biological responses, such as cell proliferation and differentiation, cell morphology …
经典且复杂的细胞信号通路：RAS/RAF/MEK/ERK - 知乎
RAS/RAF/MEK/ERK信号通路. 激活过程：细胞外的生长因子等配体与 RTKs 结合后，会引起受体的二聚化和自身磷酸化。这些磷酸化的位点可以招募包含SH2（Src Homology 2）结构域的信 …
Reactive oxygen species rescue regeneration after silencing …
2021年1月13日 · Our results suggest that (1) ROS and/or H 2 O 2 have the potential to rescue regeneration after MEK-inhibition, either by H 2 O 2 -treatment or light therapy, (2) ROS and/or …
Reactive oxygen species and cell signaling. Review
2024年2月1日 · Reactive oxygen species (ROS) activate JNK, p38 and ERK mitogen-activated protein kinases (MAPK), which upregulate c-Jun and c-Fos expression at the transcriptional …
ROS-ERK-PGE2信号通路调节皮肤损伤后早期炎症反应 - 豆丁网
2015年2月7日 · 结论 ros/erk 通过上调 cox-2 蛋白含量调节 pge2 的生成，ros-erk-cox-2/pge. 2. 信号途径参与了机械损伤后炎症反应。 关键词 活性氧、erk、环氧化酶、前列腺素e2、创面愈合 …
How ERK1/2 Activation Controls Cell Proliferation and Cell Death Is ...
Extracellular signal-regulated protein kinases 1 and 2 (ERK1/2) are members of the mitogen-activated protein kinase super family that can mediate cell proliferation and apoptosis. The …
Targeting ERK induced cell death and p53/ROS-dependent
2021年12月4日 · In a word, our results demonstrated that targeting ERK leads to cell death and p53/ROS-dependent protective autophagy simultaneously in colorectal cancer, which offers …
Nature综述：中山大学团队阐述靶向肿瘤活性氧（ROS）的原理与 …
2024年7月16日 · 低水平ros维持csc的静息状态，而高水平ros则通过刺激mapk/erk和notch1信号通路促进干细胞向增殖状态转变。静息期cscs中高水平的gsh使其对化疗和放疗不敏感。增殖 …
ROS‐ERK Pathway as Dual Mediators of Cellular Injury and …
2021年3月2日 · Urinary protein-induced ROS production triggers a cascade of phosphorylation reactions in the ERK pathway, which is a common mediator of protective autophagy and injury …
ERK调节NOX-1介导的ROS启动创面愈合中早期炎症反应的分子机 …
《ERK调节NOX-1介导的ROS启动创面愈合中早期炎症反应的分子机制》是依托上海交通大学，由王莹担任项目负责人的青年科学基金项目。 与以往对活性氧（ROS）的认识不同，最近的研 …