ROS1 is a receptor tyrosine kinase (encoded by the gene ROS1) with structural similarity to the anaplastic lymphoma kinase (ALK) protein; it is encoded by the c-ros oncogene and was first …

2024年12月25日 · ROS1 (ROS Proto-Oncogene 1, Receptor Tyrosine Kinase) is a Protein Coding gene. Diseases associated with ROS1 include Lung Cancer Susceptibility 3 and Giant …

The ROS-1 gene plays a major role in the oncogenesis of numerous tumors. ROS-1 rearrangement is found in 0.9–2.6% of non-small-cell lung cancers (NSCLCs), mostly lung …

This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type …

2025年1月4日 · This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this …

2020年8月5日 · Although previously known as c-ROS or ROS, ROS1 is now the standardized gene name. Analyses have confirmed that ROS1 encodes an evolutionarily conserved RTK …

ROS1 is a receptor tyrosine kinase that has recently been demonstrated to undergo genetic rearrangements in a variety of human cancers including glioblastoma, non-small cell lung …

ROS1, ROS proto-oncogene 1, receptor tyrosine kinase, is an orphan receptor tyrosine kinase that may activates multiple pathways involved in cell survival and transformation (PMID: …

ROS1 is proto-oncogene encoding a type I integral membrane protein with receptor tyrosine kinase (RTK) activity. ROS1 is a member of the insulin receptor family and is involved in …

2007年12月14日 · ROS1 encodes a protein tyrosine kinase with a potential transmembrane domain. It arose from the human ROS1 gene by a rearrangement introduced during gene …