2015年9月24日 · ROS activates a similar MAPK in different environmental stimuli, showing different downstream targets with different and specific responses. In animals and yeast, the mechanism behind the specific activation of MAPK by different concentration and species of ROS is elaborated, but in plants this aspect is still unclear.

ROS能诱导MAPK通路活化，研究证据分为如下3类： (1)多种细胞接受外源刺激产生ROS后，同时细胞内MAPK信号分子活化。 (2)抗氧化剂可以阻止MAPK磷酸化。

2017年4月1日 · This review will discuss the potential mechanisms by which ROS may activate and/or regulate MAPK cascades in plants. The role of MAPK cascades and ROS signaling in regulating gene expression, stomatal function, and programmed cell death (PCD) is …

One type of stress that induces potential activation of MAPK pathways is the oxidative stress caused by reactive oxygen species (ROS). Generally, increased ROS production in a cell leads to the activation of ERKs, JNKs, or p38 MAPKs, but the mechanisms by which ROS can activate these kinases are unclear.

2021年1月13日 · Our data demonstrate new relationships between regeneration-related ROS production and MAPK/ERK activation at the earliest regeneration stages, as well as the involvement of the EGFR-signaling...

2013年1月1日 · Reactive oxygen species (ROS), such as hydrogen peroxide, have been reported to activate ERKs, JNKs, and p38 MAPKs, but the mechanisms by which ROS can activate these kinases are unclear.

2015年9月23日 · FIGURE 1. Schematic representation of reactive oxygen species (ROS) regulation of mitogen activated protein kinases (MAPK) signaling pathway in biotic and abiotc stresses. ROS is a common messenger produced in response to both the stress response, acting either up- or downstream of MAPK cascade.

2017年5月1日 · MAPK, the versatile signaling molecules, crosstalk with ROS and hormones to shape acclimation responses. Plant hormones influence the acclimation response of plant to abiotic stress. ROS production and associated redox processing are an integral part of hormone regulation and function in the control of plant development and stress tolerance.

Mitogen-activated protein kinase (MAPK) signaling cascade is highly conserved across the species triggering the self-adjustment of the cells by transmitting the external signals to the nucleus.

2 天之前 · Further studies demonstrated that As2S2-treated cells exhibited ROS accumulation under fluorescence microscopy, along with activation of the P38 MAPK signaling pathway, increased apoptosis, and S-phase arrest in the cell cycle. This process could be partially reversed by the ROS inhibitor N-acetylcysteine.