U.S. Route 321 (US 321) is a spur of U.S. Route 21. It runs for 516.9 miles (831.9 km) from Hardeeville, South Carolina to Lenoir City, Tennessee; with both serving as southern termini. It reaches its northernmost point at Elizabethton, Tennessee, just northeast of Johnson City.

2005年6月17日 · U.S. 321 travels from the Piedmont of South Carolina north and northwestward to the Appalachian Mountains of eastern Tennessee. Between Gastonia and Hickory, the highway is a freeway. North of Hickory and Lenoir, U.S. 321 constitutes a four lane at-grade arterial until its ascension into the Blue Ridge Mountains.

Pennsylvania Route 321 (PA 321) is a 43.8-mile-long (70.5 km) state highway located in Elk and McKean counties in the U.S. state of Pennsylvania, maintained by the Pennsylvania Department of Transportation (PennDOT). The southern terminus is at U.S. Route 219 (US 219) in the community of Wilcox.

U.S. Route 321 is a spur of U.S. Route 21. It runs for 526 miles (847 km) from South Carolina to Tennessee. The northern terminus of U.S. 321 is between Lenoir City and Oak Ridge, Tennessee, at Interstate 40 exit 364, which is about 4 miles (6.4 km) west of Interstate 40's junction with Interstate 75.

New York State Route 321 (NY 321) is a 8.45-mile-long (13.60 km) state highway in Onondaga County, New York, in the United States. The southern terminus of the route is at an intersection with U.S. Route 20 (US 20) in the village of Skaneateles .

U.S. Route 321 is a spur of U.S. Route 21. It runs for 526 miles (847 km) from South Carolina to Tennessee. The northern terminus of U.S. 321 is between Lenoir City and Oak Ridge, Tennessee, at Interstate 40 exit 364, which is about 4 miles (6.4 km) west of Interstate 40's junction with Interstate 75.

U.S. Route 321 is a spur of U.S. Route 21. It runs for 526 miles (847 km) from South Carolina to Tennessee. The northern terminus of U.S. 321 is between Lenoir City and Oak Ridge, Tennessee, at Interstate 40 exit 364, which is about 4 miles (6.4 km) west of Interstate 40's junction with Interstate 75.

2023年5月16日 · The drive along U.S. Route 321 from Pigeon Forge to Wears Valley is about 15 minutes long, and it takes us through some of the most beautiful scenery in the region. The 8-mile route takes us...

U.S. 321 is an important route in Western North Carolina. It provides an alternative north–south route to Interstate 77, which passes through a busy metropolitan area, and US 221, which is more twisty drive up the Appalachians.

2020年8月23日 · U.S. 321 runs northeast to Greeneville, where it combines with U.S. 11E to Jonesborough and Johnson City. A short expressway section leads east from I-26/U.S. 23 toward Elizabethton. Following a circuitous route, U.S. 321 traverses areas of Cherokee National Forest by Watauga Lake to the Stone Mountains and the North Carolina line.