2024年10月8日 · Dynamic light scattering (DLS) and negative stain electron microscopy (nsEM) revealed that all eight monovalent RBD-NPs (four variants with and without Rpk9 mutations) …

RPK-9 Medvedka ("Mole cricket", NATO Designation SS-N-29) [1][2] is a modern missile system used to engage submarines. The system consists of a launcher with eight missiles, each with …

Scaled-up expression from HEK293F cells and purification by immobilized metal affinity chromatography (IMAC) and size exclusion chromatography (SEC) confirmed increased yields …

2022年11月10日 · SARS-CoV-2 S 1 has a mu-phosphatase signal peptide, mutated furin cleavage site to SGAS, D614G mutation, and Rpk9 mutations (Y365F/F392W/V395I) and …

2024年10月8日 · Pink spheres indicate β and γ RBD mutations (K417N/T, E484K, and N501Y). Purple spheres indicate stabilizing Rpk9 mutations (Y365F, F392W, and V395I). …

2021年6月1日 · Nanoparticle immunogens presenting the receptor-binding domain (RBD) of the SARS-CoV-2 Spike protein (S) in repetitive arrays are being advanced as second-generation …

Combining targeted proteomics and metabolomics suggests that acquisition of resistance in RPK9 cells is due to attenuation of dFdC phosphorylation via suppression of dCK.

2014年10月24日 · 为了向苏联海军的舰艇提供现代化的反潜 武器，它不占用太多空间，于八十年代初期启动了RPK-9项目。 新系统的开发委托给莫斯科热工学院（MIT）。 N. Mazurov成为 …

Notably, the “rpk9” combination of stabilizing mutations (Y365F, F392W, V395I) described for the Wuhan-Hu-1 RBD also enhanced yeast-surface expression of the Omicron BA.1 RBD . …

RPK-9 Medvedka ("Mole cricket", NATO Designation SS-N-29) [1] is a modern missile system used to engage submarines. The system consists of a launcher with eight missiles, each with …