Recombinant human Rpt6 protein. Isotype: IgG2b. Purity Detail: Partially purified. Source: Purified from hybridoma tissue culture supernatant. Species Reactivity: Human, Mouse, Rat. Specificity: Recognizes the Rpt6/S subunit of the 19S regulator complex. UniProt ID: P62195

Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) pH 7.4 150mM NaCl 0.02% sodium azide and 50% glycerol. The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.

Visit the supplier page for more antibody information, including target specificity, validation data, datasheets, and any potential cross-reactivities. Your search returned 11 RPT6 Antibodies across 4 suppliers. Select up to 5 products from below to compare or request more information. Biotin AF350 AF405 AF488 AF555 AF594 ...

WB dilution:1:1000 Product Description The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. Note: This product is for in vitro research use only

PSMC5/RPT6 activation by phosphorylation stimulates proteasome. Negatively regulates tight junctions (TJs) in ovarian cancer cells via CLDN3 phosphorylation. NFKB1 phosphorylation promotes NF-kappa-B p50-p50 DNA binding.

The Rpt6 (Phospho-Ser120) Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PSMC5. This antibody recognizes Human, Mouse, and Rat antigen. The Rpt6 (Phospho-Ser120) Antibody has been shown to work in the following applications: Western Blot.

2017年6月29日 · To determine if altered Rpt6 phosphorylation influences mutant Htt-induced defects in growth and the extent of protein aggregate formation, we transformed myc-RPT6, myc-rpt6-S119A and myc-rpt6-S119D strains with plasmids to induce expression of a fragment of Htt with differing polyQ lengths (Htt25Q, Htt72Q and Htt103Q) (Fig 3A).

2013年5月7日 · In this study, we use NMR spectroscopy to investigate the structure and dynamics of the Rpt6 C-terminal domain (Rpt6-C) and its interaction with assembly chaperone Rpn14. Our data demonstrate that Rpt6-C undergoes conformational exchange that is abrogated by alanine substitution of two glycines located within its two most C-terminal α helices.

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Specificity Phospho-Rpt6 (S120) Antibody detects endogenous levels of Rpt6 only when phosphorylated at S120 Immunogen Type Peptide-KLH Immunogen Description A synthesized peptide derived from human Rpt6 (Phospho-Ser120)