The human secondary somatosensory cortex (S2, SII) is a region of sensory cortex in the parietal operculum on the ceiling of the lateral sulcus. Region S2 was first described by Adrian in 1940, who found that feeling in cats' feet was not only represented in the primary somatosensory cortex (S1) but also in a second region adjacent to S1. [1]

2024年2月12日 · Combining 2-photon anatomical reconstruction with chemogenetic inhibition of specific S2 circuits, we discover that S2 projections to the secondary motor cortex (M2) govern mechanical and...

The Secondary Somatosensory Cortex, also known as S2, refers to a region in the brain that is involved in the secondary processing of sensory signals, particularly those related to touch and pain.

2023年1月24日 · In adult rodents, intense interactions between primary somatosensory cortex barrel field (S1Bf), secondary somatosensory (S2), and motor cortex (M1) are necessary for adequate detection and perception of tactile stimuli (Fassihi et al., 2017; Petersen, 2019), and reciprocal connections of S1Bf with M1 and S2 cortices underlie whisker-related ...

2021年3月31日 · Here, we report that in the secondary somatosensory cortex (S2), neurons with invariant sensory responses coexist with neurons whose responses correlate with perceptual behavior. Importantly,...

2002年9月30日 · We recorded single neurons in secondary somatosensory cortex (S2) while the monkeys performed the task. During the first stimulus period, the firing rate of S2 neurons encoded the stimulus...

Here, we investigated how primary (S1) and secondary (S2) whisker somatosensory cortex operate and interact to process tactile stimuli and their related context.

2019年1月14日 · Here, we investigated the organization of the secondary somatosensory area (S2) in the agouti (Dasyprocta aguti), a medium-sized Amazonian rodent, using microelectrode mapping techniques and neurotracer injections.

Combining 2-photon anatomical reconstruction with chemogenetic inhibition of specific S2 circuits, we discover that S2 projections to the secondary motor cortex (M2) govern mechanical and thermal sensitivity without affecting motor or cognitive function.

The functions of the secondary somatosensory cortex (S2) and insula can be inferred by evaluating the perceptual or behavioral consequences of lesions (disruptions) or direct stimulation of these anatomical sites.