Mercedes offers the sedan with either a 429-hp turbocharged 3.0-liter inline-six-cylinder engine on the S500 or a 496-hp twin-turbo 4.0-liter V-8 on the S580. Both powertrains are supplemented …

Wielding a sublime blend of comfort, performance, and prestige, the S-class remains the horse to beat in the full-size luxury sedan segment.

Browse the best April 2025 deals on 2021 Mercedes-Benz S-Class vehicles for sale. Save $24,549 this April on a 2021 Mercedes-Benz S-Class on CarGurus.

Browse the best April 2025 deals on 2021 Mercedes-Benz S-Class S 560 Coupe 4MATIC vehicles for sale. Save $26,390 this April on a 2021 Mercedes-Benz S-Class S 560 Coupe …

Save up to $16,536 on one of 233 used 2021 Mercedes-Benz S-Class Coupes near you. Find your perfect car with Edmunds expert reviews, car comparisons, and pricing tools.

Wielding a sublime blend of comfort, performance, and prestige, the S-class remains the horse to beat in the full-size luxury sedan segment.

Detailed specs and features for the Used 2021 Mercedes-Benz S-Class S 560 including dimensions, horsepower, engine, capacity, fuel economy, transmission, engine type, cylinders, …

Edmunds' expert review of the Used 2021 Mercedes-Benz S-Class provides the latest look at trim-level features and specs, performance, safety, and comfort.

Find all of our 2021 Mercedes-Benz S560 Reviews, Videos, FAQs & News in one place. Learn how it drives and what features set the 2021 Mercedes-Benz S560 apart from its rivals. Our …