2024年9月18日 · The National SARS-CoV-2 Strain Surveillance (NS3) program provides a comprehensive surveillance system for the United States to track virus evolution over time and identify emerging variants that may affect the performance of diagnostics, therapeutics, or vaccines, or that impact the transmissibility of SARS-CoV-2 or severity of COVID-19.

2024年7月1日 · As part of the CDC National SARS-CoV-2 Strain Surveillance (NS3) System, public health laboratories ship deidentified specimens to CDC to provide a representative set of viruses for sequencing. There are four main stages in the process of generating SARS-CoV-2 genetic sequence data from these specimens and making it available in public ...

The National SARS -CoV-2 Strain Surveillance (NS3) program was established in November 2020 to create a nationally representative system for baseline genomic surveillance. Through NS3, CDC has built a collection of representative SARS-CoV-2 specimens and sequences that laboratories use to

National SARS-CoV-2 Strain Surveillance (NS3) Frequently Asked Questions (Updated 08/30/2023) Why is CDC organizing this? There are multiple goals for routinely sequencing and characterizing clinical specimens that are positive for SARS-CoV-2 as part of the public health response to the COVID-19 pandemic. These can broadly be

2023年6月15日 · CDC’s national genomic surveillance system integrates SARS-CoV-2 sequences from three sources: 1) the National SARS-CoV-2 Strain Surveillance (NS3) program, † 2) CDC-contracted commercial laboratories, and 3) public sequence data repositories, including the Global Initiative on Sharing All Influenza Data (GISAID) repository and National ...

As of May 6, 2021, a total of 177,044 SARS-CoV-2 viral sequences for specimens collected during December 20, 2020–May 6, 2021 from 55 U.S. states and territories had been generated by NS3 or reported to CDC by contract laboratories; these included 3,275 sequences from specimens collected during the 2-week period ending January 2, 2021 ...

the National SARS-CoV-2 Strain Surveillance (NS3) program to provide a comprehensive and population-based U.S. surveillance system. Based on these data, sequences with similar genetic changes associated with important epidemiological and biological events are grouped into lineages* and the proportion of

Currently, the national genomic surveillance program integrates three principal sources of SARS-CoV-2 sequence data: 1) the National SARS-CoV-2 Strain Surveillance (NS3) program ¶; 2) CDC-contracted commercial sequencing data; and 3) sequences from public health, academic, and clinical laboratories that are tagged** as baseline surveillance in ...

Our study reveals a mechanism by which N-nsp3 interactions contribute to SARS-CoV-2 replication and pathogenesis but also identifies an effective antiviral therapeutic target for COVID-19. SARS-CoV-2, the causative agent of COVID-19 encodes at least 16 nonstructural proteins of variably understood function.

SARS-CoV-2 Strain Surveillance (NS3) System is incredible. NS3 continues to provide critical national SARS- CoV-2 surveillance information, increases publicly available viral sequence data, and provides specimens for isolation of viruses for phenotypic characterization, which is needed to inform how well