2024年12月25日 · SATB2 (SATB Homeobox 2) is a Protein Coding gene. Diseases associated with SATB2 include Glass Syndrome and Cleft Palate, Isolated. Among its related pathways …

SATB2 is a 733 amino-acid homeodomain-containing human protein with a molecular weight of 82.5 kDa encoded by the SATB2 gene on 2q33. The protein contains two degenerate …

2017年10月12日 · SATB2-associated syndrome (SAS) is an autosomal dominant disorder typically caused by a de novo genetic alteration (an intragenic SATB2 pathogenic variant, a …

SATB2-associated syndrome (SAS) is an autosomal dominant neurodevelopmental disorder caused by alterations in the SATB2 gene. Here we present a review of published pathogenic …

2024年1月19日 · Wahl et al. establish SATB2 as a cell-type-specific 3D genome modulator in cortical neurons. It acts independently or in cooperation with CTCF to modify the 3D genome …

The SATB2 gene encodes a nuclear matrix DNA-binding protein that specifically binds to genomic nuclear matrix attachment regions and participates in transcription regulation and chromatin …

Our findings suggest that SATB2, as measured by IHC, could serve as a promising diagnostic biomarker of CRC metastases. Combining evaluation of SATB2 with CK20 and CDX2 to form …

2013年12月4日 · SATB2 is an evolutionarily highly conserved chromatin remodeling gene located on chromosome 2q33.1. Vertebrate animal models have shown that Satb2 has a crucial role in …

SATB2 (special AT‐rich binding protein‐2) acts as a transcriptional co‐factor and modulates chromatin architecture to regulate gene expression. The purpose of this review was to discuss …

SATB2-associated syndrome is caused by genetic changes that affect the SATB2 gene. These include changes within the SATB2 gene itself and deletions of large pieces of DNA from …