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Baseline total metabolic tumor volume combined with …
New volume-based parameters derived from baseline 18 F-FDG PET/CT, such as total metabolic tumor volume (TMTV) and total lesion glycolysis (TLG), can reflect metabolic volume and activity and have been proposed as quantitative indexes of tumor metabolism biomarkers in Hodgkin’s and B-cell lymphomas [8].
TMTV-Net: fully automated total metabolic tumor volume
2024年2月8日 · Total metabolic tumor volume (TMTV) segmentation has significant value enabling quantitative imaging biomarkers for lymphoma management. In this work, we tackle the challenging task of automated tumor delineation in lymphoma from PET/CT scans using a cascaded approach. Our study included 1418 2-[18F]FDG …
肿瘤基线代谢参数预测弥漫大B细胞淋巴瘤预后的价值
基线肿瘤代谢指标包括最大葡萄糖标准摄取值(SUVmax)、平均摄取值(SUVmean)、总肿瘤代谢体积(TMTV)、总糖酵解率(TLG)。 分析肿瘤代谢参数及临床和血液学相关指标对治疗的影响。 结果 51例患者中,20例复发或进展,中位无进展生存(PFS)期时间为12.0个月(1.0~64.0个月),2年PFS率为25.5%(13/51)。 TMTV、TLG与血清乳酸脱氢酶(LDH)水平的相关性较强。 单因素分析显示Ann Arbor分期、NCCN-IPI评分、TMTV均对预后有显著相关 …
文献荐读之血液肿瘤|景红梅主编力荐:高基线总肿瘤代谢体积(TMTV…
2020年7月23日 · 通过PRT-CT扫描并应用41%的最大标准化摄取值阈值法计算出的总肿瘤代谢体积(TMTV)可以评估肿瘤负荷,并且已经证实与霍奇金淋巴瘤,滤泡性淋巴瘤和未治疗的DLBCL的预后相关。 本研究通过对REMARC临床试验(NCT01122472)来评估基线TMTV是否对R-CHOP治疗有效的老年患者是否具有预后价值。 方法. 在REMARC临床试验中,经过6或8个周期的标准R-CHOP治疗后获得CR或PR的650名60-80岁老年DLBCL患者被随机分配1:1分别给予 …
A deep learning model for automated total metabolic tumor …
2024年6月1日 · We developed an end-to-end deep learning (DL) model for automatic lesion segmentation and TMTV quantification from FDG-positron emission tomography/computed tomography (FDG-PET/CT) scans.
TMTV-Net demonstrates strong performance and generalizability in TMTV segmentation across multi-site external datasets, encompassing various lymphoma subtypes.
TMTV-Net: Fully Automated Total Metabolic Tumor Volume ... - GitHub
This repository employs a deep-learning method for the automated segmentation of total metabolic tumor volume (TMTV) in whole-body [18]F-FDG PET/CT images, with an emphasis on multi-center generali...
TMTV-Net: fully automated total metabolic tumor volume …
Total metabolic tumor volume (TMTV) segmentation has significant value enabling quantitative imaging biomarkers for lymphoma management. In this work, we tackle the challenging task of automated tumor delineation in lymphoma from PET/CT scans using a cascaded approach.
血浆ctDNA T790M突变和总代谢肿瘤体积对晚期EGFR突变NSCLC …
分析血浆循环肿瘤DNA(circulating tumor DNA, ctDNA)T790M突变和总代谢肿瘤体积(total metabolic tumor volume, TMTV)在经酪氨酸激酶抑制剂(tyrosine kinase inhibitors, TKIs)治疗的晚期表皮生长因子受体(epidermal growth factor receptor, EGFR)突变非小细胞肺癌(non-small cell lung cancer, NSCLC)患者预后中 ...