2024年12月25日 · SIRT2 (Sirtuin 2) is a Protein Coding gene. Diseases associated with SIRT2 include Thrombocytopenia and Retinoblastoma. Among its related pathways are Cell Cycle, …

Sirtuin 2 (SIRT2) is an NAD+-dependent deacetylase that was under studied compared to other sirtuin family members. SIRT2 is the only sirtuin protein which is predominantly found in the …

Sirtuin 2 (SIRT2), as a member of the sirtuin family, has representative features of evolutionarily highly conserved nicotinamide adenine dinucleotide (NAD+)-dependent deacetylase activity. …

2022年12月29日 · Sirtuins (SIRTs) are nicotine adenine dinucleotide (+)-dependent histone deacetylases regulating critical signaling pathways in prokaryotes and eukaryotes, and are …

Human sirtuin 2 (SIRT2) is an NAD +-dependent deacetylase that primarily functions in the cytoplasm, where it can regulate α-tubulin acetylation levels. SIRT2 is linked to cancer …

As a type of nicotinamide adenine dinucleotide (NAD +)-dependent deacetylases, sirtuin 2 (SIRT2) is predominantly found in the cytoplasm of cells in the central nervous system (CNS), …

2020年2月10日 · This study demonstrates that SIRT2 is actively transported into the nucleus via a process regulated by its C-terminus and provides a resource of SIRT2 interacting partners.

2004年4月28日 · Silent information regulator 2 (Sir2) proteins, or sirtuins, are protein deacetylases dependent on nicotine adenine dinucleotide (NAD) and are found in organisms …

Sirtuin 2 (Sirt2) is a member of the sirtuin family of NAD-dependent lysine deacylases and plays important roles in regulation of the cell cycle and gene expression. As a nucleocytoplasmic …

SIRT2 inhibits colony formation in glioma cell lines (Hiratsuka et al., 2003) and arrests chromosomal instability by getting down-regulated. SIRT2 is associated with …