Systemic lupus erythematosus (SLE) affects several organs (such as skin, joints and kidneys) and blood tests reveal circulating autoantibodies. The clinical features of SLE are highly variable and may overlap with other diseases and conditions. Skin involvement or cutaneous lupus (CLE) affects 80% of patients with SLE.

2021年7月27日 · Lupus arthritis most often affects joints that are farther from the middle of your body, like your fingers, wrists, elbows, knees, ankles, and toes. Lupus arthritis is less likely to cause permanent joint damage than rheumatoid arthritis. Tendonitis is inflammation in the tendons — the tissues that connect your muscles to your bones.

2024年7月17日 · The most common type of lupus is systemic lupus erythematosus (SLE). This condition can cause dactylitis, also known as “sausage fingers,” which makes the fingers swell and feel tight. Swollen fingers can happen with lupus-related joint inflammation or other issues like arthritis or tendinitis.

Nonspecific fatigue, fever, arthralgia, and weight changes are the most common symptoms in new cases or recurrent active SLE flares. Fatigue, the most common constitutional symptom associated with SLE, can be due to active SLE, medications, lifestyle habits, or concomitant fibromyalgia or affective disorders.

Chronic cutaneous (discoid) lupus erythematosus is usually diagnosed when someone exhibits signs of lupus in the skin. People with SLE can also have discoid lesions, and about 5% of all people with DLE will develop SLE later in life.

2022年2月9日 · Physical examination showed dozens of 1–2 mm yellowish-white hard nodules on her fingerpads (Fig. 1). Initially, we assumed that she had developed skin calcifications. Blood tests revealed low estimated glomerular filtration rate (29 ml/min/1.73 m …

What is cutaneous lupus erythematosus? Cutaneous lupus erythematosus (LE) is a diverse group of autoimmune connective tissue disorders localised to the skin that can be associated with systemic lupus erythematosus (SLE) to varying degrees. Cutaneous lupus erythematosus (CLE) is …

Some people with lupus develop a condition called Raynaud's phenomenon. Their fingers and toes become painful, numb, and tingly in response to cold temperatures or emotional stress. This happens...

2025年1月17日 · Lupus lesions on the nail fold (the base of the nail where it grows from the finger) appear to be the source of many nail-related lupus problems, including ridges and splitting in the nail plate (the hard surface of the nail). Nail redness or redness/discoloration around the nails could be due to problems with blood vessels.

2024年6月18日 · The most common locations for the skin lesions of systemic lupus erythematosus include the: Face, especially the cheeks and nose. Sun-exposed skin on the arms, backs of hands, upper chest, and upper back due to increased sensitivity to sunlight (photosensitivity). Fingers and fingernails. Inside the mouth or nose. Scalp.