Biomarkers play a crucial role in diagnosing SLE, classifying SLE complications, assessing SLE disease activity, and reflecting the therapeutic effect of interventions for SLE. Common …

In recent years, newly discovered potential biomarkers have great research potential in the diagnosis, disease activity prediction, and treatment of systemic lupus erythematosus (SLE). …

This clinical heterogeneity of SLE poses a great demand for biomarkers that can differentiate, determine, monitor, stratify and/or predict organ-specific involvement in patients with SLE. Of …

Systemic lupus erythematosus (SLE) is an inflammatory autoimmune disease characterized by diverse autoantibodies and varied clinical features. There is much interest in biomarkers, but …

2024年8月21日 · Systemic lupus erythematosus (SLE) is a chronic inflammatory disease that has protean manifestations and follows a relapsing and remitting course. More than 90% of...

2021年6月22日 · This article reviews clinical and immunological biomarkers that could diagnose and monitor disease activity in SLE, with and without organ-specific injury. In addition, novel …

Introduction: Systemic lupus erythematosus (SLE) is a heterogeneous and chronic autoimmune disease. Aberrant DNA methylation occurs during various processes of SLE development …

2020年6月1日 · Routine laboratory markers of inflammation are limited to ESR, anemia and proteinuria. Cytokines, S100 proteins and urinary lymphocytes could qualify for future …

While systemic lupus erythematosus (SLE) is an autoantibody and immune complex disease by nature, most of its organ manifestations are in fact inflammatory. SLE activity scores thus …

2019年9月1日 · To discover biomarkers for SLE, a phage displayed random peptide library (Ph.D. 12) and deep sequencing were applied to screen specific autoantibodies in a total of 100 …