2023年1月9日 · Prostate-specific membrane antigen (PSMA)-directed posi-tron emission tomography/computed tomography (PET/CT) is a non-invasive diagnostic technique to image PSMA posi-tive lesions in individuals with prostate cancer. PSMA is a transmembrane protein with an extracellular binding site.

This document provides guidance and standards for the indication, acquisition, and interpretation of PSMA PET/CT for prostate cancer imaging.

Here we aim to provide updated guidance and standards for the indication, acquisition, and interpretation of PSMA PET/CT for prostate cancer imaging. Procedures and characteristics are reported for a variety of available PSMA small radioligands.

Prostate-specific membrane antigen (PSMA) is expressed by the majority of clinically significant prostate adenocarcinomas, and patients with target-positive disease can easily be identified by PSMA PET imaging.

The dosimetry for both 68Ga-PSMA-11 and 18F-DCFPyL is comparable to that of other radiotracers in terms of whole-body exposure (Table 1). 68Ga-PSMA-11 has a calculated effective dose of 0.017 mSv/MBq, equating to 4.4 mSv for a 259 MBq (7 mCi) injected dose, with the highest uptake organ being the kidney at 0.37 mGy/MBq (11). The total effective ...

2023年1月27日 · Prostate-specific membrane antigen (PSMA) is expressed by the majority of clinically significant prostate adenocarcinomas, and patients with target-positive disease can easily be identified by PSMA PET imaging.

2017年3月10日 · 68 Ga-PSMA positron emission tomography/computed tomography (PET/CT) is a non-invasive diagnostic technique to image prostate cancer with increased prostate-specific membrane antigen (PSMA, glutamate carboxypeptidase II, EC 3.4.17.21) expression. PSMA is a transmembrane protein primarily present in all prostatic tissues.

Prostate-specific membrane antigen (PSMA) is expressed by the majority of clinically significant prostate adenocarcinomas, and patients with target-positive disease can easily be identified by PSMA PET imaging. Promising results with PSMA-targeted radiopharmaceutical therapy have already been obtain …

前列腺特异性膜抗原 (psma) 由大多数具有临床意义的前列腺腺癌表达，靶标阳性疾病的患者可以通过 psma pet 成像轻松识别。 在使用靶向分子和放射性标记物的各种组合的早期研究中，已经获得了 PSMA 靶向放射性药物治疗的有希望的结果。

Prostate-specific membrane antigen (PSMA)-directed positron emission tomography/computed tomography (PET/CT) is a non-invasive diagnostic technique to image PSMA positive lesions in individuals with prostate cancer. PSMA is a transmembrane protein with an …