2020年12月16日 · Treatment cost update sourcing Ebselen (also called SPI-1005) from China: Has anyone tried to get Ebselen (SPI-1005) online? Monthly treatment cost with the Ebselen now is similar to AVs. There is still no FDA approval for treating MD with Ebselen nor with AVs, but a lot of us tried AVs and were having success, so why not to try Ebselen?

2023年1月17日 · SPI-1005 for the Treatment of Meniere's Disease - Full Text View - ClinicalTrials.gov . Jan 25, 2023 #5. ...

2012年1月26日 · SEATTLE, Nov. 5, 2013 /PRNewswire/ -- Sound Pharmaceuticals (SPI) has successfully completed enrollment of its Phase 2 clinical trial with SPI-1005 at the University of Florida. This study enrolled 80 healthy subjects with normal or slight hearing loss and exposed the volunteer to calibrated music using an iPod®and insert earphones.

2022年8月19日 · This is the original SPI-1005 study for Meniere's Disease. They put it on hold during Covid while they ran other SPI-1005 studies. But now looks like it's actually recruiting.

2012年1月26日 · SPI-1005 almost certainly won't reverse any hearing loss you've already experienced, but there is a chance it might help prevent further progression depending on the underlying pathology. It is also being tested for the prevention of acute noise-induced hearing loss, and since it works for Meniere's disease as well, that suggests a possible ...

2012年1月26日 · On day 84, the SPI-1005 group showed a significant rate of WIN improvement of 54.4% over placebo (42.1% vs. 27.1%, p=0.0336). During OLE, responder rates involving LFPTA and WIN continued to improve, and patient reported outcome measures for tinnitus, vertigo, aural fullness, and dizziness severity all improved significantly from baseline (≥ ...

2012年1月26日 · SEATTLE — SPI-1005 hits pre-specified endpoints resulting in a significant improvement in hearing loss of 65% and 95% relative to placebo Sound Pharmaceuticals today announced positive top-line results from a randomized, double-blind, placebo-controlled, multi-center Phase 2b study in Meniere's Disease (MD).

2012年1月26日 · Even though I don't have Meniere's, I'm bumping this so SPI-1005 will get noticed by those of us who do have Meniere's disease involving tinnitus. SPI-1005 looks to be the next drug on the horizon for us to try. I still have a tiny bit of hope left even after the recent, highly disappointing failures from Frequency Therapeutics, followed by ...

2012年1月26日 · It seems Sound Pharmaceuticals are actually at the point of being able to lodge this, although I am not sure if it is delayed further due to the issues around COVID-19, or due to the fact that there have been big changes and developments in what happens with SPI-1005, especially since Sound Pharmaceuticals ended up adding the COVID-19 ...

2023年1月17日 · I was in chaos and wanted it stopped. My ENT never gave me the option. I started doing my own research on anything and everything Meniere's as I wasn't getting info from the specialists. I think I stay strong with the support of my wife and church family. If SPI-1005 doesn't do the trick, I will attempt to start antivirals. 2 hours South, huh?