Pathway干货 | NF-Kb 信号通路简介 - 知乎 - 知乎专栏
NF-kB信号通路. NF-kB在细胞因子诱导的基因表达中起关键性的调控作用，它调控的基因编码急性期反应蛋白、细胞因子、细胞粘附分子、免疫调节分子、病毒瘤基因、生长因子、转录和生长 …
NF-κB in biology and targeted therapy: new insights and …
2024年3月4日 · In this review, we first scrutinize the research process of NF-κB signaling, and summarize the composition, activation, and regulatory mechanism of NF-κB signaling. We …
Essential role of Src-family protein tyrosine kinases in NF-κB ...
2003年2月3日 · Our data show the existence of a functionally distinct SFK signaling module responsible for pre-BCR–mediated NF-κB activation and B cell development. Expression of …
快速了解NF-κB 通路 - 知乎 - 知乎专栏
NF-κB （Nuclear Factor kappa-light-chain-enhancer of activated B cells）通路是一种在细胞信号传递中极为重要的途径，它在 调控免疫反应 、 炎症反应 、 细胞生长与死亡 等多种生理过程 …
Syk/Src/NF-κB axis is essentially targeted in anti ... - PubMed
2024年11月24日 · These findings suggest that an ethanol extract of Bletilla striata could be developed as a promising natural anti-inflammatory drug or health functional food with NF-κB …
The therapeutic targeting of the FGFR1/Src/NF-κB signaling axis ...
2018年7月9日 · We showed that ALDH high (ALDH+) pancreatic cancer cells exhibited stem cell-like phenotype and expressed higher levels of FGFR1, Src, NF-κB, alongside stemness …
NF-κB in biology and targeted therapy: new insights and
2024年3月4日 · In this review, we first scrutinize the research process of NF-κB signaling, and summarize the composition, activation, and regulatory mechanism of NF-κB signaling. We …
The Regulation of NF-κB Subunits by Phosphorylation - PMC
The NF-κB transcription factor is the master regulator of the inflammatory response and is essential for the homeostasis of the immune system. NF-κB regulates the transcription of …
Interaction of SRC-1 with NF-kB. | Download Scientific Diagram
In this study, we investigated recruitment of coactivators (SRC-1, SRC-2, and SRC-3) and corepressors (HDAC1, HDAC2, HDAC3, SMRT, and NCoR) to the IkappaB alpha gene …
Regulation of NF-κB Activation by MAP Kinase Cascades
1997年12月1日 · Activation of NF-KB is mediated through the phosphorylation of its inhibitory subunit IKB, followed by the subsequent degradation of IKE at the proteasome. A second level …