STAT3 (STAT3)靶点介绍及实验小贴士| Abcam中文官网
stat3是一个信号转导和转录激活子，介导细胞对白介素、kitlg/scf、lep和其他生长因子的反应。 一旦被激活，会 将共激活剂（例如NCOA1或MED1）募集到目标基因的启动子区域。
Stat3 Antibody - Cell Signaling Technology
3 天之前 · Polyclonal Antibody for studying STAT3. Validated for ChIP, IHC, IP, WB. Highly specific and rigorously validated in-house, Stat3 Antibody (CST #9132) is ready to ship.
请教，STAT3和p-STAT3 Western Blot蛋白检测 - 丁香通研选
2023年3月1日 · STAT3 Western Blot蛋白检测，一般提取的蛋白是总蛋白。 根据实验需要你也可以提取特定蛋白。 通常情况下， STAT3 Western Blot检测所用的蛋白质提取物是包括细胞核、细胞质和细胞膜的总蛋白质。 这是因为 STAT3是一种细胞内信号传导蛋白，存在于多种细胞结构中，因此要检测其全局表达水平，需要提取包括细胞核、细胞质和细胞膜的总蛋白质。 在文献中，通常报道的是磷酸化状态的STAT3 (p-STAT3)含量的变化情况，而不是总的STAT3含量。 这是 …
STAT3 antibody (10253-2-AP) | Proteintech - ptglab
Very good Stat3 antibody for western blot. Strong signal at 1:5000 dilution. Highly recommend. Applications: Western Blot, Primary Antibody Dilution: 1:5000; Cell Tissue Type: Hela
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靶点解惑Plus | 热门MAPK-ERK/JAK-STAT/Myc信号通路讲解，附带相关靶点的WB …
1 天前 · stat3通过诱导g1期到s期进程的关键基因的表达参与细胞周期调控，如ccnd1。 stat3在lep激活下可能通过反式激活birc5表达发挥凋亡作用。 stat3作为众多致癌信号通路的汇聚点，在调节抗肿瘤免疫反应中发挥着核心作用。il-6是最经典的stat3激活剂。
Phospho-Stat3 (Tyr705) Antibody | Cell Signaling Technology
3 天之前 · Polyclonal Antibody for studying STAT3 (Tyr705) phosphate. Validated for ChIP, IP, WB, WB. Available in 2 sizes. Highly specific and rigorously validated in-house, Phospho-Stat3 (Tyr705) Antibody (CST #9131) is ready to ship.
STAT3 antibody (80149-1-RR) | Proteintech - ptglab
80149-1-RR targets STAT3 in WB, ELISA applications and shows reactivity with human, mouse samples. PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
Anti-STAT3抗体[9D8] (ab119352) - Abcam中文官网
Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene (PubMed:17344214). May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.
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jak2/stat3通路的qpcr和wb检测具体包括包括哪些？-丁香实验
2023年2月13日 · stat3（信号转导和转录激活因子3）：是一种转录因子，能够调节基因的转录，参与细胞的增殖、分化、凋亡和免疫应答等生物学过程。 socs（抑制器蛋白）：是一组负调节蛋白，能够抑制jak2/stat3通路的信号转导和转录活性，维持细胞内的稳态。
Quantification of total and phosphorylated STAT3 by
2023年9月5日 · Here, we describe quantification of the expression and phosphorylation of the transcription factor STAT3. We present isolation of total and phosphorylated STAT3 from cell lysates by immunoprecipitation, followed by SDS-PAGE and western blot together with known amounts of a calibrator protein that shares an epitope with the precipitated proteins.