
Interplay between mTOR and STAT5 signaling modulates the …
Together, these findings indicate that the dynamic interaction between mTOR and STAT5 signaling modulates the reciprocal differentiation of the effective and regulatory T cells, and …
奶牛乳腺上皮细胞JAK2-STAT5和mTOR信号通路协同调控乳蛋白 …
通过瞬时转染RNAi方法,分别对AKT1和STAT5基因进行基因沉寂,检测AKT1、STAT5和mTOR在mRNA和蛋白质表达以及活性磷酸化状态变化,并进一步综述对奶牛乳腺上皮细胞β …
mTOR direct crosstalk with STAT5 promotes de novo lipid
2019年8月14日 · Here, we demonstrate that liver-specific activation of mTORC1 promoted the expression of lipid synthesis genes and lead to the development of spontaneous HCC. …
Intersection of mTOR and STAT signaling in immunity
2015年1月1日 · STAT5 and mTOR signaling events differentially regulate effector and memory Tc cell survival, and a balance between the functions of these pathways may be required for …
mTOR direct crosstalk with STAT5 promotes de novo lipid ... - PubMed
2019年8月14日 · In conclusion, our data suggested that mTORC1 upregulates SREBP1 transcription via crosstalk with the STAT5 pathway which contributes to the NAFLD-related …
In conclusion, our data suggested that mTORC1 upregulates SREBP1 transcription via crosstalk with the STAT5 pathway which contributes to the NAFLD-related HCC pathogenesis. And the …
Blood:mTOR通过减少STAT5对IRF8的抑制调节骨髓单核细胞发育…
2018年2月23日 · 近日有研究人员通过scid小鼠、mtor缺陷小鼠、混合嵌合体小鼠和体外菌落形成以及单核/巨噬细胞诱导试验发现,抑制mtor可导致cd11b+f4/80+细胞的数量和比例降低,以 …
A central role for STAT5 in the transcriptional programing of
2022年11月25日 · STAT5 controlled transcription of members of the mTOR pathway to license T cells for IL-2–mediated mTOR signaling and promoted MYC-driven metabolic changes. …
Intersection of mTOR and STAT signaling in immunity - Cell …
2014年11月15日 · STAT5 and mTOR signaling events differentially regulate effector and memory Tc cell survival, and a balance between the functions of these pathways may be required for …
Interplay between mTOR and STAT5 signaling modulates the …
2015年4月1日 · In this study, we show that there is direct interaction between mTOR and STAT5 signaling in both Tregs and Teffs: mTOR inhibition weakens Teffs growth, but make Tregs shift …
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