SUV39H1 - Wikipedia
Histone-lysine N-methyltransferase SUV39H1 is an enzyme that in humans is encoded by the SUV39H1 gene. [5] This gene is a member of the suppressor of variegation 3-9 homolog …
SUV39H1 Gene - GeneCards | SUV91 Protein | SUV91 Antibody
2024年12月25日 · SUV39H1 (SUV39H1 Histone Lysine Methyltransferase) is a Protein Coding gene. Diseases associated with SUV39H1 include Hyperoxaluria, Primary, Type I and …
Structure, Activity and Function of the Suv39h1 and Suv39h2
2021年7月16日 · SUV39H1 and SUV39H2 were the first protein lysine methyltransferases that were identified more than 20 years ago. Both enzymes introduce di- and trimethylation at …
Disruption of SUV39H1-Mediated H3K9 Methylation Sustains CAR …
2024年1月12日 · We show here that the genetic disruption of SUV39H1, which encodes a histone-3, lysine-9 methyl-transferase, enhances the early expansion, long-term persistence, …
Establishment of H3K9-methylated heterochromatin and its
2021年5月13日 · Suppressor of variegation 3–9 homologue 1 (SUV39H1) and SUV39H2 are often recruited to chromatin by non-coding RNA (ncRNA), or in worms by endogenous siRNA …
SUV39H1 SUV39H1 histone lysine methyltransferase [ (human)]
SUV39H1 is a prognosis and immune microenvironment-related biomarker in diffuse large B-cell lymphoma. Decreased SUV39H1 at the promoter region leads to increased CREMalpha and …
SUV39H1 epigenetically modulates the MCPIP1-AURKA signaling …
2024年9月19日 · In this study, we conducted a high-throughput screen utilizing a compound library containing 288 epigenetic drugs, leading to the identification of chaetocin as the most …
The methyltransferase Suv39h1 links the SUMO pathway to …
2016年7月18日 · Our results establish an unexpected feature of Suv39h1, distinct from the KMT activity, with a major role for heterochromatin formation. We discuss how linking Suv39h1 to …
SUV39H1 maintains cancer stem cell chromatin state and
2025年3月10日 · We identify SUV39H1, a histone-3, lysine-9 methyltransferase, as critical for GSC maintenance and GBM progression. SUV39H1 is upregulated in GBM compared with …
SUV39H1 is a New Client Protein of Hsp90 Degradated by …
SUV39H1 mediates epigenetic events in the pathophysiology of hematopoietic disorders. We found that inhibition of Hsp90 by Chaetocin and 17-AAG had ability to induce degradation of …