SW620 [SW-620] is an adherent cell line isolated from the large intestine of a Dukes C colorectal cancer patient. This cell line is highly tumorigenic and has applications in gastrointestinal (GI), cancer, and drug research.

Classification of human colorectal adenocarcinoma cell lines.

2013年9月12日 · Using a couple of isogenic human colon cancer cell lines derived either from the primary tumor (SW480) or from a lymph node metastasis (SW620), we found that only SW480 cells were sensitive to ...

Human SW620 cells were isolated from a patient with a colorectal adeno-carcinoma, from a lymph node as metastatic site. As routine quality controls, the cells are regularly checked for Mycoplasma contamination and authenticity (via STR DNA Typing). During surgery, tumors cells are implanted into the caecum, a part of the colon compartment.

SW620; Culture Type: Cell line ; Keywords: Human Colorectal Adenocarcinoma Cell Line ; Description: Established from a 51 years old Caucasian male patient with Dukes C colorectal adenocarcinoma; Origin: Organism: Species: Human (Homo sapiens) Age: 51 years; Ethnicity: Caucasian; Gender: Male; Tissue: Large intestine, Colon

SW620 cells harvested from tissue culture flasks are implanted into the subcutaneous space of the left flank of the mice. Resulting tumors are monitored by calipering twice weekly. Animal weights are measured three times weekly. Animal behaviour is monitored daily.

SW620 cells harvested from tissue culture flasks are implanted into the subcutaneous space or into the mammary fat pad (subQperior) of the left flank of the mice. Resulting tumors are monitored by calipering twice weekly.

2016年3月3日 · In the present study, we demonstrated miR-145 downregulation in SW620 colon cancer cells and found that expression of miR-145 in normal human colonic epithelial cells was five times higher than that in SW620 cells.

SW620 Xenograft Model. Xenograft animal models are used to assess the effectiveness of drugs against specific types of cancer. New medicines are tested on staged tumor growths that have been engrafted via subcutaneous or orthotopic inoculation in an immunocompromised mouse or …

SW620 is a human colon cancer cell line that was established from a lymph node metastasis of a primary colon adenocarcinoma. Colorectal cancer is the third most common cancer worldwide, and adenocarcinomas account for the majority of cases.